Traumatic brain injuries

K Blennow, DL Brody, PM Kochanek, H Levin… - Nature reviews Disease …, 2016 - nature.com
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …

The new neurometabolic cascade of concussion

CC Giza, DA Hovda - Neurosurgery, 2014 - journals.lww.com
Since the original descriptions of postconcussive pathophysiology, there has been a
significant increase in interest and ongoing research to study the biological underpinnings of …

A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury

ME Shenton, HM Hamoda, JS Schneiderman… - Brain imaging and …, 2012 - Springer
Mild traumatic brain injury (mTBI), also referred to as concussion, remains a controversial
diagnosis because the brain often appears quite normal on conventional computed …

Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury

AC McKee, RC Cantu, CJ Nowinski… - … of Neuropathology & …, 2009 - academic.oup.com
Since the 1920s, it has been known that the repetitive brain trauma associated with boxing
may produce a progressive neurological deterioration, originally termed dementia …

Translational research in traumatic brain injury

D Laskowitz, G Grant - 2016 - books.google.com
Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

White matter damage and cognitive impairment after traumatic brain injury

KM Kinnunen, R Greenwood, JH Powell, R Leech… - Brain, 2011 - academic.oup.com
White matter disruption is an important determinant of cognitive impairment after brain injury,
but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor …

Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia

SK Song, SW Sun, WK Ju, SJ Lin, AH Cross… - Neuroimage, 2003 - Elsevier
Both axon and myelin degeneration have significant impact on the long-term disability of
patients with white matter disorder. However, the clinical manifestations of the neurological …

A decade of DTI in traumatic brain injury: 10 years and 100 articles later

MB Hulkower, DB Poliak… - American Journal …, 2013 - Am Soc Neuroradiology
The past decade has seen an increase in the number of articles reporting the use of DTI to
detect brain abnormalities in patients with traumatic brain injury. DTI is well-suited to the …

Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients

A Vanhaudenhuyse, Q Noirhomme, LJF Tshibanda… - Brain, 2010 - academic.oup.com
The 'default network'is defined as a set of areas, encompassing posterior-
cingulate/precuneus, anterior cingulate/mesiofrontal cortex and temporo-parietal junctions …

Demyelination increases radial diffusivity in corpus callosum of mouse brain

SK Song, J Yoshino, TQ Le, SJ Lin, SW Sun, AH Cross… - Neuroimage, 2005 - Elsevier
Myelin damage, as seen in multiple sclerosis (MS) and other demyelinating diseases,
impairs axonal conduction and can also be associated with axonal degeneration. Accurate …