With emerging drug delivery technologies becoming accessible, more options are expected
to become available to patients with glioblastoma (GBM) in the near future. It is important for …

Background Proper catheter placement for convection-enhanced delivery (CED) is required
to maximize tumor coverage and minimize exposure to healthy tissue. We developed an …

Thanks to the recent advances in the development of chemotherapeutics, the morbidity and
mortality of many cancers has decreased significantly. However, compared to oncology in …

Convection-enhanced delivery (CED) has been proposed as a treatment option for a wide
range of neurological diseases. Neuroinfusion catheter CED allows for positive pressure …

Gene supplementation and editing for neurodegenerative disorders has emerged in recent
years as the understanding of the genetic mechanisms underlying several …

Convection-enhanced drug delivery (CED) directly infuses drugs with a large molecular
weight toward target cells as a therapeutic strategy for neurodegenerative diseases and …

Background Convection enhanced delivery (CED) is emerging as a promising infusion
toolto facilitate delivery of therapeutic agents into the brain via mechanically controlled …

The efficacy of convection-enhanced delivery as a technique to treat disorders of the central
nervous system is limited by backflow, in which the infused fluid flows backward along …

Background Acute convection-enhanced delivery (CED) is a neurosurgical delivery
technique that allows for precise and uniform distribution of an infusate to a brain structure. It …

Convection-enhanced delivery (CED) is a technique to bypass the blood-brain barrier and
deliver therapeutic agents into the brain. However, animal studies and preliminary clinical …