RF Krall, T Tzounopoulos, E Aizenman - Neuroscience, 2021 - Elsevier
Nearly sixty years ago Fredrich Timm developed a histochemical technique that revealed a rich reserve of free zinc in distinct regions of the brain. Subsequent electron microscopy …
R Sun, J Wang, J Feng, B Cao - Biomolecules, 2022 - mdpi.com
Zinc, an essential micronutrient for life, was first discovered in 1869 and later found to be indispensable for the normal development of plants and for the normal growth of rats and …
Vesicular transporters (VTs) define the type of neurotransmitter that synaptic vesicles (SVs) store and release. While certain mammalian neurons release multiple transmitters, it is not …
L Martínez-Parra, M Piñol-Cancer, C Sanchez-Cano… - ACS …, 2023 - ACS Publications
Atherosclerosis is a complex disease that can lead to life-threatening events, such as myocardial infarction and ischemic stroke. Despite the severity of this disease, diagnosing …
Abstract Zinc (Zn 2+) is an essential micronutrient that is required for a wide variety of cellular processes. Tools and methods have been instrumental in revealing the myriad roles …
JH Ha, O Prela, DR Carpizo, SN Loh - Frontiers in Molecular …, 2022 - frontiersin.org
A large percentage of transcription factors require zinc to bind DNA. In this review, we discuss what makes p53 unique among zinc-dependent transcription factors. The …
NK Isaev, EV Stelmashook… - Reviews in the …, 2020 - degruyter.com
The disruption of homeostasis of zinc (Zn2+) and copper (Cu2+) ions in the central nervous system is involved in the pathogenesis of many neurodegenerative diseases, such as …
Zinc is an essential micronutrient required for all domains of life. Cells maintain zinc homeostasis using a network of transporters, buffers, and transcription factors. Zinc is …
Zinc is a highly abundant cation in the brain, essential for cellular functions, including transcription, enzymatic activity, and cell signaling. However, zinc can also trigger injurious …