Liquid-liquid phase separation (LLPS) can drive a multitude of cellular processes by compartmentalizing biological cells via the formation of dense liquid biomolecular …
A Bratek-Skicki, M Van Nerom, D Maes… - Advances in Colloid and …, 2022 - Elsevier
Biomolecular condensates are membraneless, intracellular organelles that form via liquid- liquid phase separation (LLPS) and have the ability to concentrate a wide range of …
Membrane wetting by biomolecular condensates recently emerged as a key phenomenon in cell biology, playing an important role in a diverse range of processes across different …
A Avni, A Joshi, A Walimbe, SG Pattanashetty… - Nature …, 2022 - nature.com
Biomolecular condensates formed via liquid-liquid phase separation (LLPS) are involved in a myriad of critical cellular functions and debilitating neurodegenerative diseases …
Liquid-liquid phase separation or LLPS of proteins is a field of mounting importance and the value of quantitative kinetic and thermodynamic characterization of LLPS is increasingly …
K Kitamura, A Oshima, F Sasaki… - The Journal of …, 2024 - ACS Publications
We examined the effects of trimethylamine N-oxide (TMAO) and urea (known osmolytes) on the liquid–liquid phase separation (LLPS) of fused in sarcoma (FUS) and three FUS-LLPS …
Y Huang, N Wang, J Wang, X Ji, J Yang… - Industrial & …, 2023 - ACS Publications
Effectively regulating the liquid–liquid phase separation (LLPS) phenomenon in the process of molecular self-assembly is critical for controlling the qualities of the final products …
Y Ma, H Li, Z Gong, S Yang, P Wang… - Journal of the American …, 2022 - ACS Publications
RNA molecules with repeat expansion sequences can phase separate into gel-like condensate, which could lead to neurodegenerative diseases. Here, we report that, in the …
K Yokosawa, S Kajimoto, D Shibata… - The Journal of …, 2022 - ACS Publications
Liquid–liquid phase separation (LLPS) is an important phenomenon in biology, and it is desirable to develop quantitative methods to analyze protein droplets generated by LLPS …