A molecular view of DNA flexibility

A Marin-Gonzalez, JG Vilhena, R Perez… - Quarterly Reviews of …, 2021 - cambridge.org
DNA dynamics can only be understood by taking into account its complex mechanical
behavior at different length scales. At the micrometer level, the mechanical properties of …

DNA in nanochannels: theory and applications

K Frykholm, V Müller, KK Sriram… - Quarterly Reviews of …, 2022 - cambridge.org
Nanofluidic structures have over the last two decades emerged as a powerful platform for
detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …

Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions

SE Farr, EJ Woods, JA Joseph, A Garaizar… - Nature …, 2021 - nature.com
Liquid–liquid phase separation (LLPS) is an important mechanism that helps explain the
membraneless compartmentalization of the nucleus. Because chromatin compaction and …

Sequence-dependent persistence lengths of DNA

JS Mitchell, J Glowacki, AE Grandchamp… - Journal of chemical …, 2017 - ACS Publications
A Monte Carlo code applied to the cgDNA coarse-grain rigid-base model of B-form double-
stranded DNA is used to predict a sequence-averaged persistence length of l F= 53.5 nm in …

Full Site‐Specific Addressability in DNA Origami‐Templated Silica Nanostructures

LM Wassermann, M Scheckenbach… - Advanced …, 2023 - Wiley Online Library
DNA nanotechnology allows for the fabrication of nanometer‐sized objects with high
precision and selective addressability as a result of the programmable hybridization of …

Dependence of DNA persistence length on ionic strength and ion type

S Guilbaud, L Salomé, N Destainville, M Manghi… - Physical review …, 2019 - APS
Even though the persistence length LP of double-stranded DNA plays a pivotal role in cell
biology and nanotechnologies, its dependence on ionic strength I lacks a consensual …

DNA mechanics and its biological impact

A Basu, DG Bobrovnikov, T Ha - Journal of molecular biology, 2021 - Elsevier
Almost all nucleoprotein interactions and DNA manipulation events involve mechanical
deformations of DNA. Extraordinary progresses in single-molecule, structural, and …

Probing the mechanical properties, conformational changes, and interactions of nucleic acids with magnetic tweezers

F Kriegel, N Ermann, J Lipfert - Journal of structural biology, 2017 - Elsevier
Nucleic acids are central to the storage and transmission of genetic information. Mechanical
properties, along with their sequence, both enable and fundamentally constrain the …

Partition complex structure can arise from sliding and bridging of ParB dimers

L Connolley, L Schnabel, M Thanbichler… - Nature …, 2023 - nature.com
In many bacteria, chromosome segregation requires the association of ParB to the parS-
containing centromeric region to form the partition complex. However, the structure and …

How do polymers stretch in capillary-driven extensional flows?

V Calabrese, AQ Shen, SJ Haward - Macromolecules, 2024 - ACS Publications
Measurements of the capillary-driven thinning and breakup of fluid filaments are widely used
to extract the extensional rheological properties of complex materials. For viscoelastic fluids …