Analytical methods and biological activities of Panax notoginseng saponins: Recent trends

C Xu, W Wang, B Wang, T Zhang, X Cui, Y Pu… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Panax notoginseng (Burk.) FH Chen, also called
Sanqi, is a widely used traditional Chinese medicine, which has long history used as herbal …

Focus on notoginsenoside R1 in metabolism and prevention against human diseases

H Liu, J Yang, W Yang, S Hu, Y Wu… - Drug Design …, 2020 - Taylor & Francis
Abstract Notoginsenoside (NG)-R1 is one of the main bioactive compounds from Panax
notoginseng (PN) root, which is well known in the prescription for mediating the micro …

Therapeutic Candidates for Alzheimer's Disease: Saponins

R Zhang, M Zeng, X Zhang, Y Zheng, N Lv… - International Journal of …, 2023 - mdpi.com
Drug development for Alzheimer's disease, the leading cause of dementia, has been a long-
standing challenge. Saponins, which are steroid or triterpenoid glycosides with various …

Pro-angiogenic activity of notoginsenoside R1 in human umbilical vein endothelial cells in vitro and in a chemical-induced blood vessel loss model of zebrafish in vivo

B Yang, S Hong, SMY Lee, W Cong, J Wan… - Chinese journal of …, 2016 - Springer
Objective This study aimed at investigating whether notoginsenoside R1 (R1), a unique
saponin found in Panax notoginseng could promote angiogenic activity on human umbilical …

Monoclonal antibodies and immunoassay for medical plant-derived natural products: a review

X Yan, Y Zhao, Y Zhang, H Qu - Molecules, 2017 - mdpi.com
Owing to the widespread application value, monoclonal antibodies (MAbs) have become a
tool of increasing importance in modern bioscience research since their emergence …

Immunological separation of bioactive natural compounds from crude drug extract and its application for cell-based studies

T Uto, T Ohta, S Fujii, Y Shoyama - Antibodies, 2021 - mdpi.com
In this study, we present a review on a useful approach, namely, immunoaffinity column
coupled with monoclonal antibodies (MAbs), to separate natural compounds and its …

Notoginsenoside R1 induces DNA damage via PHF6 protein to inhibit cervical carcinoma cell proliferation

T Cai, W Wu, L Guo, Y Xia, X Jiang… - Molecular …, 2021 - spandidos-publications.com
Abstract Notoginsenoside R1 (NGR1), a monomer of Traditional Chinese medicine, is from
the Panax notoginsenoside complex, and has been reported to inhibit the proliferation of …

Studies on natural products using monoclonal antibodies: a review

Y Shoyama - Antibodies, 2021 - mdpi.com
An immunoblotting system (“eastern blotting”) was developed for small-molecule herbal
medicines like glycosides, with no conjugation function to the membrane. Briefly, the crude …

A new strategy for the preparation of antibody against natural glycoside: With astragaloside IV as an example

CX Chen, L Dai, HY Feng, L Wang, K Guo, LS Ding… - Fitoterapia, 2020 - Elsevier
A new strategy for the hapten design of natural glycoside and application for the preparation
of antibody is reported in this work. With astragaloside IV (AGS-IV) as an example, C6”-CH 2 …

[HTML][HTML] Generation of monoclonal antibodies against natural products

Y Zhang, P Cao, F Lu, X Yan… - JoVE (Journal …, 2019 - www-jove-com-443.vpn.cdutcm.edu …
The analysis of the bioactive components present in foods and natural products has become
a popular area of study in many fields, including traditional Chinese medicine and food …