Paracoccidioidomycosis (PCM), initially reported in 1908 in the city of São Paulo, Brazil, by
Adolpho Lutz, is primarily a systemic and neglected tropical mycosis that may affect …

Fungal disease is an increasingly recognised global clinical challenge associated with high
mortality. Early diagnosis of fungal infection remains problematic due to the poor sensitivity …

The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …

Amphotericin B deoxycholate, a key member of the polyene antifungal class, has been a
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …

The global diversity of fungi has been estimated between 2 to 11 million species, of which
only about 155 000 have been named. Most fungi are invisible to the unaided eye, but they …

Amphotericin B deoxycholate, a key member of the polyene antifungal class, has been a
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …

Amphotericin B deoxycholate, a key member of the polyene antifungal class, has been a
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …

Amphotericin B deoxycholate, a key member of the polyene antifungal class, has been a
cornerstone in the treatment of invasive fungal infections for over five decades. Despite its …

Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America caused by
thermodimorphic fungi of the genus Paracoccidioides. In the last two decades, enhanced …

In the search for new antifungal agents, a novel series of fifteen hydrazine-thiazole
derivatives was synthesized and assayed in vitro against six clinically important Candida …