Macrocyclic scaffolds are commonly found in bioactive natural products and pharmaceutical
molecules. So far, a large number of macrocyclic natural products have been isolated and …

Cyclic molecular frameworks, especially the benzannulated medium-sized and macrocyclic
ring (BMR) systems, constitute an integral component of a large number of biologically …

Macrocyclic compounds are of growing interest because of their natural existence, their
interesting biological, physicochemical properties, and potential applications in medicine. 1 …

A macrocyclic Cu-catalyzed Sonogashira-type cross-coupling reaction has been developed
that employs an operationally simple CuCl/phen/Cs2CO3 catalyst system. Macrocyclizations …

We present an efficient synthetic pathway for kasugamycin, an aminoglycoside antibiotic,
utilizing naturally derived carbohydrates as starting materials. This synthesis effectively …

A set of nine trans-disubstituted dihydropyran-based medium ring macrolides has been
synthesized using d-glucal as chiral pool and evaluated against a panel of three human …

A fast, solvent-free solid acid mediated synthetic strategy for the synthesis of
bisindolylmethanes has been developed. The process is applicable to a wide range of …

Aryl bromides and 4‐chlorotoluene as an example aryl chloride in the presence of N‐
heterocyclic carbene (NHC) palladium hydroxo dimers of the type [{Pd (μ‐OH) Cl (NHC)} …

Logical manipulation of protecting groups is one of the vital strategies involved in the
synthesis of complex oligosachharides. As opposed to the robust permanent protecting …

Therapeutic immunoadjuvants have been derived through a straightforward glycosylation of
various alcohols with unprotected and non-activated monosaccharides, under solvent free …