Radiolabelling of nanomaterials for medical imaging and therapy
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
medical imaging and therapy. Over the last two decades, there has been an increasing effort …
Analysis of nanoparticle delivery to tumours
Targeting nanoparticles to malignant tissues for improved diagnosis and therapy is a
popular concept. However, after surveying the literature from the past 10 years, only …
popular concept. However, after surveying the literature from the past 10 years, only …
Meta-analysis of nanoparticle delivery to tumors using a physiologically based pharmacokinetic modeling and simulation approach
Numerous studies have engineered nanoparticles with different physicochemical properties
to enhance the delivery efficiency to solid tumors, yet the mean and median delivery …
to enhance the delivery efficiency to solid tumors, yet the mean and median delivery …
[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy
B Surekha, NS Kommana, SK Dubey… - Colloids and Surfaces B …, 2021 - Elsevier
Abstract Poly (amidoamine) dendrimers (PAMAM) are novel polymeric highly branched
architectures with well-defined nano-size, narrow polydispersity index and numerous active …
architectures with well-defined nano-size, narrow polydispersity index and numerous active …
Transepithelial transport and toxicity of PAMAM dendrimers: implications for oral drug delivery
S Sadekar, H Ghandehari - Advanced drug delivery reviews, 2012 - Elsevier
This article summarizes efforts to evaluate poly (amido amine)(PAMAM) dendrimers as
carriers for oral drug delivery. Specifically, the effect of PAMAM generation, surface charge …
carriers for oral drug delivery. Specifically, the effect of PAMAM generation, surface charge …
Targeted photodynamic therapy–a promising strategy of tumor treatment
AM Bugaj - Photochemical & Photobiological Sciences, 2011 - pubs.rsc.org
Targeted therapy is a new promising therapeutic strategy, created to overcome growing
problems of contemporary medicine, such as drug toxicity and drug resistance. An emerging …
problems of contemporary medicine, such as drug toxicity and drug resistance. An emerging …
Therapeutic implications of nanomedicine for ocular drug delivery
Delivering therapeutics to the eye is challenging on multiple levels: rapid clearance of
eyedrops from the ocular surface requires frequent instillation, which is difficult for patients; …
eyedrops from the ocular surface requires frequent instillation, which is difficult for patients; …
Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration
Retinal neuroinflammation, mediated by activated microglia, plays a key role in the
pathogenesis of photoreceptor and retinal pigment epithelial cell loss in age-related macular …
pathogenesis of photoreceptor and retinal pigment epithelial cell loss in age-related macular …