Transition-metal-catalyzed reductive amination employing hydrogen

T Irrgang, R Kempe - Chemical Reviews, 2020 - ACS Publications
The reductive amination, the reaction of an aldehyde or a ketone with ammonia or an amine
in the presence of a reducing agent and often a catalyst, is an important amine synthesis …

Polyoxometalate (POM)-based crystalline hybrid photochromic materials

L Li, YT Yu, NN Zhang, SH Li, JG Zeng, Y Hua… - Coordination Chemistry …, 2024 - Elsevier
As discrete anionic metal–oxygen clusters, polyoxometalates (POMs) demonstrate immense
advantages as photochromic materials owing to their good redox properties and photo …

Nickel-catalyzed hydrogenative coupling of nitriles and amines for general amine synthesis

VG Chandrashekhar, W Baumann, M Beller… - Science, 2022 - science.org
Efficient and general methods for the synthesis of amines remain in high demand in the
chemical industry. Among the many known processes, catalytic hydrogenation is a cost …

Ruthenium-Catalyzed N-Alkylation of Amines with Alcohols under Mild Conditions Using the Borrowing Hydrogen Methodology

AB Enyong, B Moasser - The Journal of organic chemistry, 2014 - ACS Publications
Using a simple amino amide ligand, ruthenium-catalyzed one-pot alkylation of primary and
secondary amines with simple alcohols was carried out under a wide range of conditions …

Continuous‐Flow Synthesis of (R)‐Tamsulosin Utilizing Sequential Heterogeneous Catalysis

Y Saito, K Nishizawa, B Laroche, H Ishitani… - Angewandte …, 2022 - Wiley Online Library
We describe the continuous‐flow synthesis of (R)‐tamsulosin, a blockbuster therapeutic
drug employed for dysuria associated with urinary stones and benign prostatic hyperplasia …

Recent achievements in the hydrogenation of nitriles catalyzed by transitional metals

K Lévay, L Hegedűs - Current Organic Chemistry, 2019 - ingentaconnect.com
Amines are important and valuable intermediates in the pharmaceutical, plastic and
agrochemical industry. Hence, there is an increasing interest in developing improved …

A mild hydration of nitriles catalysed by copper (II) acetate

P Marcé, J Lynch, AJ Blacker… - Chemical …, 2016 - pubs.rsc.org
A simple, mild and general procedure for the hydration of nitriles to amides using copper as
catalyst and promoted by N, N-diethylhydroxylamine is described. The reaction can be …

Cooperative molybdenum-thiolate reactivity for transfer hydrogenation of nitriles

SF Hou, JY Chen, M Xue, M Jia, X Zhai, RZ Liao… - ACS …, 2019 - ACS Publications
A half-sandwich molybdenum (II) thiolate complex with a η2-MeCN ligand, Cp* Mo (1, 2-
Ph2PC6H4S)(η2-NCMe)(1 (η2-NCMe)), was found to catalyze transfer hydrogenation of …

Direct Reductive Amination of Carbonyl Compounds with H2 Using Heterogeneous Catalysts in Continuous Flow as an Alternative to N‐Alkylation with Alkyl Halides

B Laroche, H Ishitani… - Advanced Synthesis & …, 2018 - Wiley Online Library
A general continuous‐flow procedure for direct reductive amination of secondary and
primary amines with aromatic and aliphatic aldehydes as well as ketones is reported. The …

One-pot reductive amination of aldehydes with nitroarenes over an Au/Al 2 O 3 catalyst in a continuous flow reactor

EA Artiukha, AL Nuzhdin, GA Bukhtiyarova… - Catalysis Science & …, 2015 - pubs.rsc.org
One-pot reductive amination of aromatic and aliphatic aldehydes with nitroarenes over an
Au/Al2O3 catalyst in a continuous flow reactor using molecular hydrogen as a reducing …