As traditional strategies for cancer treatment, some chemotherapy agents, such as
doxorubicin, oxaliplatin, cyclophosphamide, bortezomib, and paclitaxel exert their anti-tumor …

Natural killer cells are members of the innate immune system and promote cytotoxic activity
against tumor or infected cells independently from MHC recognition. NK cells are modulated …

Background Mitoxantrone (MTX) is a synthetic compound used as a second line
chemotherapeutic drug for prostate cancer. It has been reported to trigger immunogenic cell …

Accumulating evidence shows that the anti-cancer potential of the immune response that
can be activated by modulation of the immunogenicity of dying cancer cells. This regulated …

Colorectal cancer (CRC) is one of the most frequent and deadly forms of cancer. About half
of patients are affected by metastasis, with the cancer spreading to eg, liver, lungs or the …

Ferroptosis is an iron-and reactive oxygen species-dependent form of regulated cell death
with great clinical translational potential for cancer treatment, however, the efficacy of …

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. Oxidative
phosphorylation (OXPHOS) has attracted a considerable attention in CRC. It is of great …

Immunological checkpoint inhibitors provide a revolutionary method for cancer treatment.
However, due to low tumor mutations and insufficient infiltration of immune cells into the …

Modulating the immunosuppressive tumor microenvironment (TME) while enhancing
antitumor immune responses is a promising strategy. In this study, we designed an acid …

The insertion of a molecule between the bases of DNA is known as intercalation. A molecule
is able to interact with DNA in different ways. DNA intercalators are generally aromatic …