Reviews the properties of cloned glutamate receptors (GR) and the role of native receptors
in brain diseases and brain injuries. Substantiation for the detrimental role of these receptors …

Glutamate receptor (GluR) channels play major roles in fast excitatory synaptic transmission.
Based on the pharmacological properties, GluR channels have been classified into three …

ACTIVATION of the N-methyl-d-aspartate (NMDA) receptor is important for certain forms of
activity-dependent synaptic plasticity, such as long-term potentiation (reviewed in ref. 1), and …

Vicini, Stefano, Jian Feng Wang, Jin Hong Li, Wei Jian Zhu, Yue Hua Wang, Jian Hong Luo,
Barry B. Wolfe, and Dennis R. Grayson. Functional and pharmacological differences …

Forty years of research into the function of l-glutamic acid as a neurotransmitter in the
vertebrate central nervous system (CNS) have uncovered a tremendous complexity in the …

Developmental and regional alternative splicing of the NMDAR1 subunit gene transcript was
examined by in situ hybridization in the developing and adult rat brain. NMDAR1 mRNA …

The function of the N-methyl-D-aspartate (NMDA)-preferring glutamate receptor can be
regulated by extracellular pH, a process that may be important during ischemia in the brain …

We have determined the gene structure for the NMDA receptor subunit gene NMDAR1. We
found eight splice variants that arise from different combinations of a single 5'terminal exon …

The NMDA-type glutamate receptor mediates because of its proposed role in brain
development, excitatory transmission in the brain. The NMDA learning and memory and the …

The properties of many ligand-gated ion channels are altered during development. We have
characterized a developmental switch in the sensitivity of NMDA receptors to the novel …