A variety of cognitive disorders are worsened by stress exposure and involve dysfunction of
the newly evolved prefrontal cortex (PFC). Exposure to acute, uncontrollable stress …

This review examines mechanisms contributing to the intergenerational transmission of self-
regulation. To provide an integrated account of how self-regulation is transmitted across …

Post-traumatic stress disorder (PTSD) is the only major mental disorder for which a cause is
considered to be known: that is, an event that involves threat to the physical integrity of …

Research on the neurobiology of the stress response in animals has led to successful new
treatments for Post-Traumatic Stress Disorder (PTSD) in humans. Basic research has found …

Mood, motivation, attention, and arousal are behavioral states having a profound impact on
cognition. Behavioral states are mediated though the peripheral nervous system and …

The prefrontal cortex (PFC)—the most evolved brain region—subserves our highest-order
cognitive abilities. However, it is also the brain region that is most sensitive to the detrimental …

Acute stress shifts the brain into a state that fosters rapid defense mechanisms. Stress-
related neuromodulators are thought to trigger this change by altering properties of large …

An update to the classic text that links neuroscience and human behavior in the context of
therapy. This groundbreaking book explores the recent revolution in psychotherapy that has …

Here we provide a review of the animal and human literature concerning the role of the
amygdala in fear conditioning, considering its potential influence over autonomic and …

OBJECTIVE: Most research on the effects of severe psychological stress has focused on
stress-related psychopathology. Here, the author develops psychobiological models of …