Solution nuclear magnetic resonance (NMR) spectroscopy is a powerful tool to study
structures and dynamics of biomolecules under physiological conditions. As there are …

Advancement in drug therapies and patient care have drastically improved the mortality
rates of HIV-1 infected individuals. Many of these therapies were developed or improved …

During the late phase of HIV type 1 (HIV-1) infection cycle, the virally encoded Gag
polyproteins are targeted to the inner leaflet of the plasma membrane (PM) for assembly …

Abstract Phosphatidylinositol 4, 5-bisphosphate (PIP2) is critical for HIV-1 virus assembly.
The viral membrane is enriched in PIP2, suggesting that the virus assembles at PIP2-rich …

During the late phase of the HIV-1 replication cycle, the viral Gag polyproteins are targeted
to the plasma membrane for assembly. The Gag-membrane interaction is mediated by …

Human immunodeficiency virus type 1 (HIV-1) trans-activator of transcription (Tat) is a small,
intrinsically disordered basic protein that plays diverse roles in the HIV-1 replication cycle …

During the late phase of HIV-1 infection, viral Gag polyproteins are targeted to the plasma
membrane (PM) for assembly. Gag localization at the PM is a prerequisite for the …

Retroviral Gag targeting to the plasma membrane (PM) for assembly is mediated by the N-
terminal matrix (MA) domain. For many retroviruses, Gag–PM interaction is dependent on …

Assembly of human T-cell leukemia virus type 1 (HTLV-1) particles is initiated by the
trafficking of virally encoded Gag polyproteins to the inner leaflet of the plasma membrane …

Retroviral assembly is a highly coordinated step in the replication cycle. The process is
initiated when the newly synthesized Gag and Gag-Pol polyproteins are directed to the inner …