Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Alphaherpesviruses like herpes simplex virus are large DNA viruses characterized by their
ability to establish lifelong latent infection in neurons. As for all herpesviruses …

Bioinspired organ-level in vitro platforms are emerging as effective technologies for
fundamental research, drug discovery, and personalized healthcare. In particular, models for …

Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that
has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA …

To ensure their homeostasis and sustain differentiated functions, cells continuously transport
diverse cargos to various cell compartments and in particular to the cell surface. Secreted …

Herpes simplex virus type 1 (HSV-1) is a neuroinvasive human pathogen that has the ability
to infect and replicate within epithelial cells and neurons and establish a life-long latent …

Microtubules (MTs) form a rapidly adaptable network of filaments that radiate throughout the
cell. These dynamic arrays facilitate a wide range of cellular processes, including the …

Viruses are obligate intracellular pathogens that are dependent on cellular machineries for
their replication. Recent technological breakthroughs have facilitated reliable identification …

The natural history of oral herpes simplex virus type 1 (HSV‐1) infection in the
immunocompetent host is complex and rich in controversial phenomena, namely the role of …

Herpesviral pathogenesis stems from infection of multiple cell types including the site of
latency and cells that support lytic replication. Herpesviruses utilize distinct cellular …