Male fertility has deteriorated over the last decades, and environmental risk factors are
among the possible causes of this phenomenon. Pollutants such as heavy metals might …

Acute kidney injury (AKI) is a clinical syndrome characterized by a rapid and significant
decrease in renal function that can arise from various etiologies, and is associated with high …

Mammalian sperm, the only cells that achieve their purpose outside their organism of origin,
have to swim vigorously within the female reproductive tract to reach an oocyte. Flagellar …

STUDY QUESTION Are epididymosomes implicated in protein transfer from the epididymis
to spermatozoa? SUMMARY ANSWER We characterized the contribution of epididymal …

Spermatozoa acquire their fertilizing ability and forward motility during epididymal transit,
suggesting the importance of the epididymis. Although the cell atlas of the epididymis was …

Regulatory T cells (Tregs) modulate tissue homeostatic processes and immune responses.
Understanding tissue-Treg biology will contribute to developing precision-targeting …

Background Previous research has illustrated the role of cilia as mechanical and sensory
antennae in various organs within the mammalian male reproductive system across different …

The development and maintenance of the correct morphology of sperm is important for their
functions. Cellular morphogenesis of sperm occurs during the post-meiotic developmental …

The epididymis functions as transition zone for post-testicular sperm maturation and storage
and faces contrasting immunological challenges, ie tolerance towards spermatozoa vs …

Introduction One of the most intriguing aspects of male reproductive physiology is the ability
of the epididymis to prevent the mounting of immune responses against the onslaught of …