Polymeric amorphous solid dispersion (ASD) is a popular approach for enhancing the
solubility of poorly water-soluble drugs. However, achieving both physical stability and …

Membrane crystallization (MCr) is a novel coupling technique, where the membrane can act
as the interface of heterogeneous nucleation, aiming to reduce the nucleation barrier and …

The oral delivery of genistein (GEN) is hindered by its low bioavailability. The delivery of
tetramethylpyrazine (TMP or ligustrazine) is faced with physical instability challenges due to …

The anionic surfactant sodium lauryl sulfate (SLS) is known to deteriorate the dissolution of
some drugs by forming poorly soluble lauryl sulfate (LS) salts. However, because of the …

In vitro drug release testing is an important quality control tool for formulation development.
However, the literature has evidence that poly-lactide-co-glycolide (PLGA)-based …

Dimetronidazole (DMZ), an veterinary antibiotic, exhibits poor photostability with only
80.38% potency remaining after exposure to illuminance of 4500 lux for 7 days. The …

The use of the surfactant, sodium lauryl sulfate (SLS), instead of enhancing drug dissolution,
deteriorates the dissolution of some alkaline drugs through forming poorly soluble lauryl …

Apsorpcija lekovite supstance iz gastrointestinalnog trakta zavisi od brojnih meĎusobno
povezanih fizičkohemijskih, fizioloških, biofarmaceutskih i farmaceutsko-tehnoloških faktora …

Dissolution in gastrointestinal tract (GI tract) is critical for oral solid dosage forms, especially
for drugs with poor solubility. Among the commonly used approaches, applications of …