Kaposi sarcoma (KS) gained public attention as an AIDS-defining malignancy; its
appearance on the skin was a highly stigmatizing sign of HIV infection during the height of …

The chemokine receptors CXCR1/2 and their ligand CXCL8 are essential for the activation
and trafficking of inflammatory mediators as well as tumor progression and metastasis. The …

Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

Cervical cancer (CC) is the third most common carcinoma and the fourth leading cause of
cancer-associated mortality in women. Here, we report that MDM2-DHX9 interaction …

MicroRNAs (miRNAs) are short single-stranded non-coding RNA sequences that
posttranscriptionally regulate up to 60% of protein encoding genes. Evidence is emerging …

Chronic inflammation is recognized as a threat factor for cancer progression. Release of
inflammatory molecules generates microenvironment which is highly favorable for …

G protein-coupled receptor kinase 2 (GRK2) is a central signaling node involved in the
modulation of many G protein-coupled receptors (GPCRs) and also displaying regulatory …

Accumulating evidence indicates that G protein-coupled receptor kinase 2 (GRK2) is a
versatile protein that acts as a signaling hub by modulating G protein-coupled receptor …

Viruses have evolved a multitude of mechanisms to combat barriers to productive infection
in the host cell. Virally-encoded miRNAs are one such means to regulate host gene …

Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus-8
(HHV-8), is etiologically linked to the development of Kaposi's sarcoma, primary effusion …