Lifelong indices of maladaptive behavior or illness often stem from early physiological
aberrations during periods of dynamic development. This is especially true when …

Insulin‐like growth factor‐I (IGF‐I) signaling plays a key role in neuroinflammation. Here we
show that IGF‐1 also regulates phagocytosis of reactive astrocytes through p110α isoform of …

Despite decades of stress research, there still exist substantial gaps in our understanding of
how social, environmental, and biological factors interact and combine with developmental …

Disparities in socio-economic status (SES) predict many immune system-related diseases,
and previous research documents relationships between SES and the immune cell …

It has long been hypothesized that attractiveness provides a cue to a target's health and
immunocompetence. However, much of the research testing this hypothesis has relied on a …

Increasing age is associated with dysregulated immune function and increased
inflammation—patterns that are also observed in individuals exposed to chronic social …

Much research indicates that exposure to early life adversity (ELA) predicts chronic
inflammatory activity, increasing one's risk of developing diseases of aging later in life …

Background Although early adversity is now recognized as a major public health concern, it
remains unclear if the effects of early-life stressors on disease biology and health differ by …

Background Depression results from interactions between biological, social, and
psychological factors. Literature shows that depression is associated with abnormal brain …

Although seasonal changes in physiology are well documented, little is known about how
human immune and metabolic markers vary across seasons, and no studies have examined …