Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss

R Kirwan, D McCullough, T Butler, F Perez de Heredia… - GeroScience, 2020 - Springer
The COVID-19 pandemic is an extraordinary global emergency that has led to the
implementation of unprecedented measures in order to stem the spread of the infection …

Vitamin D deficiency and sarcopenia in older persons

F Remelli, A Vitali, A Zurlo, S Volpato - Nutrients, 2019 - mdpi.com
Vitamin D deficiency is a common health problem worldwide, in particular among older
people. Vitamin D regulates and modulates the physiology and function of multiple human …

Vitamin D and sarcopenia: potential of vitamin D supplementation in sarcopenia prevention and treatment

R Uchitomi, M Oyabu, Y Kamei - Nutrients, 2020 - mdpi.com
Skeletal muscle, the largest organ in the human body, accounting for approximately 40% of
body weight, plays important roles in exercise and energy expenditure. In the elderly, there …

Sarcopenia, osteoporosis and frailty

E Gielen, J Dupont, M Dejaeger, MR Laurent - Metabolism, 2023 - Elsevier
Muscles and bones are intricately connected tissues displaying marked co-variation during
development, growth, aging, and in many diseases. While the diagnosis and treatment of …

Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update

GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
Sarcopenia is generally an age-related condition that directly impacts the quality of life. It is
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …

Osteosarcopenia: A case of geroscience

B Kirk, A Al Saedi, G Duque - Aging Medicine, 2019 - Wiley Online Library
Many older persons lose their mobility and independence due to multiple diseases
occurring simultaneously. Geroscience is aimed at developing innovative approaches to …

Health effects of vitamin D supplementation: lessons learned from randomized controlled trials and mendelian randomization studies

R Bouillon, MS LeBoff, RE Neale - Journal of Bone and Mineral …, 2023 - academic.oup.com
Vitamin D plays an important role in calcium homeostasis and many cellular processes.
Although vitamin D supplements are widely recommended for community‐dwelling adults …

[HTML][HTML] Overexpression of the vitamin D receptor (VDR) induces skeletal muscle hypertrophy

JJ Bass, A Nakhuda, CS Deane, MS Brook… - Molecular …, 2020 - Elsevier
Abstract Objective The Vitamin D receptor (VDR) has been positively associated with
skeletal muscle mass, function and regeneration. Mechanistic studies have focused on the …

Genetic variants, serum 25-hydroxyvitamin D levels, and sarcopenia: A mendelian randomization analysis

T Sha, Y Wang, Y Zhang, NE Lane, C Li… - JAMA Network …, 2023 - jamanetwork.com
Importance Vitamin D deficiency is commonly associated with sarcopenia; however, the
latest International Clinical Practice Guidelines for Sarcopenia do not recommend vitamin D …

Vitamin D deficiency in older patients—problems of sarcopenia, drug interactions, management in deficiency

M Kupisz-Urbańska, P Płudowski… - Nutrients, 2021 - mdpi.com
Vitamin D deficiency frequently occurs in older people, especially in individuals with
comorbidity and polypharmacotherapy. In this group, low vitamin D plasma concentration is …