A dynamic DNA tetrahedron framework for active targeting

T Tian, T Zhang, S Shi, Y Gao, X Cai, Y Lin - Nature Protocols, 2023 - nature.com
An active targeting strategy-enabled DNA tetrahedron delivery vehicle could facilitate stable
drug encapsulation and stimuli-responsive on-demand release, building a universal …

Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics

P Song, LR Wu, YH Yan, JX Zhang, T Chu… - Nature biomedical …, 2022 - nature.com
Cell-free DNA (cfDNA) in the circulating blood plasma of patients with cancer contains
tumour-derived DNA sequences that can serve as biomarkers for guiding therapy, for the …

Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples

L Wang, X Wang, Y Wu, M Guo, C Gu, C Dai… - Nature Biomedical …, 2022 - nature.com
The detection of samples at ultralow concentrations (one to ten copies in 100 μl) in biofluids
is hampered by the orders-of-magnitude higher amounts of 'background'biomolecules. Here …

Solid-state nanochannels for bio-marker analysis

Y Huang, L Liu, C Luo, W Liu, X Lou, L Jiang… - Chemical Society …, 2023 - pubs.rsc.org
Bio-markers, such as ions, small molecules, nucleic acids, peptides, proteins and cells,
participate in the construction of living organisms and play important roles in biological …

DNA-framework-based multidimensional molecular classifiers for cancer diagnosis

F Yin, H Zhao, S Lu, J Shen, M Li, X Mao, F Li… - Nature …, 2023 - nature.com
A molecular classification of diseases that accurately reflects clinical behaviour lays the
foundation of precision medicine. The development of in silico classifiers coupled with …

[HTML][HTML] Regulation of exosome production and cargo sorting

H Wei, Q Chen, L Lin, C Sha, T Li, Y Liu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment

T Zhang, T Tian, R Zhou, S Li, W Ma, Y Zhang, N Liu… - Nature protocols, 2020 - nature.com
Although organic nanomaterials and inorganic nanoparticles possess inherent flexibility,
facilitating functional modification, increased intracellular uptake and controllable drug …

DNA walkers for biosensing development

L Song, Y Zhuge, X Zuo, M Li, F Wang - Advanced Science, 2022 - Wiley Online Library
The ability to design nanostructures with arbitrary shapes and controllable motions has
made DNA nanomaterials used widely to construct diverse nanomachines with various …

Direct SARS-CoV-2 nucleic acid detection by Y-shaped DNA dual-probe transistor assay

D Kong, X Wang, C Gu, M Guo, Y Wang… - Journal of the …, 2021 - ACS Publications
Rapid screening of infected individuals from a large population is an effective means in
epidemiology, especially to contain outbreaks such as COVID-19. The gold standard assays …

Surface plasmon resonance (SPR) biosensors for food allergen detection in food matrices

J Zhou, Q Qi, C Wang, Y Qian, G Liu, Y Wang… - Biosensors and …, 2019 - Elsevier
Food allergies are recognized as a growing public health concern, with an estimated 3% of
adults and 6-8% of children affected by food allergy disorders. Hence, food allergen …