Nanopore technology is a promising label-free detection method. However, challenges exist
for its further application in sequencing, clinical diagnostics and ultra-sensitive single …

The amino-acid sequence of a protein encodes information on its three-dimensional
structure and specific functionality. De novo design has emerged as a method to manipulate …

Abstract Biosensor is a device that responds to a particular target in a selective way by
incorporation of biological recognition as sensing unit. For practical biomedical applications …

The interaction between nanoparticles dispersed in a fluid and nanopores is governed by
the interplay of hydrodynamical, electrical, and chemical effects. We developed a theory for …

Nanopore sensing has attracted much attention as a rapid, simple, and label-free single-
molecule detection technology. To apply nanopore sensing to extensive targets including …

Nanopore sensing is a versatile technique for the analysis of molecules on the single-
molecule level. However, extracting information from data with established algorithms …

This paper describes a method for detecting microRNA (miRNA) expression patterns using
the nanopore-based DNA computing technology. miRNAs have shown promise as markers …

Although DNA computation has traditionally been developed for parallel calculations in
molecular analyses, this approach has recently been considered for use in diagnostic or …

This paper describes a strategy for simultaneous recognition of over-and under-expressed
microRNAs (miRNAs) using the method of signal classification-based nanopore decoding …

Characteristic ionic current modulations will be produced in a single molecule manner
during the communication of individual molecules with a nanopore. Hence, the information …