Reinventing (bio) chemical analysis with paper

GIJ Salentijn, M Grajewski, E Verpoorte - Analytical chemistry, 2018 - ACS Publications
This paper focuses on one of the most commonly encountered materials in our society,
namely paper. Paper is an inherently complex material, yet its use provides for chemical …

Paper‐based electrochemical sensors and how to make them (work)

W Mazurkiewicz, M Podrażka, E Jarosińska… - …, 2020 - Wiley Online Library
Paper‐based devices are said to be easy to make and use. It is true, if you know how. We
hope this Review will help people that are new to the field but also those more experienced …

An off-the-shelf multi-well scaffold-supported platform for tumour organoid-based tissues

NT Li, NC Wu, R Cao, JL Cadavid, S Latour, X Lu… - Biomaterials, 2022 - Elsevier
Complex 3D bioengineered tumour models provide the opportunity to better capture the
heterogeneity of patient tumours. Patient-derived organoids are emerging as a useful tool to …

A pH-sensing optode for mapping spatiotemporal gradients in 3D paper-based cell cultures

RM Kenney, MW Boyce, NA Whitman… - Analytical …, 2018 - ACS Publications
Paper-based cultures are an emerging platform for preparing 3D tissue-like structures.
Chemical gradients can be imposed upon these cultures, generating microenvironments …

Evaluation of hybrid vesicles in an intestinal cell model based on structured paper chips

P De Dios Andres, IN Westensee, E Brodszkij… - …, 2021 - ACS Publications
Cell culture-based intestinal models are important to evaluate nanoformulations intended for
oral drug delivery. We report the use of a floating structured paper chip as a scaffold for …

based Transwell assays: an inexpensive alternative to study cellular invasion

RM Kenney, A Loeser, NA Whitman, MR Lockett - Analyst, 2019 - pubs.rsc.org
Cellular movement is essential in the formation and maintenance of healthy tissues as well
as in disease progression such as tumor metastasis. In this work, we describe a paper …

Developing novel in vitro methods for the risk assessment of developmental and placental toxicants in the environment

RC Fry, J Bangma, J Szilagyi, JE Rager - Toxicology and applied …, 2019 - Elsevier
During pregnancy, the placenta is critical for the regulation of maternal homeostasis and
fetal growth and development. Exposures to environmental chemicals during pregnancy can …

Triple-Barrel Ultramicroelectrodes for Multipurpose, Submilliliter Electroanalysis

PJ Kauffmann, NL Walker, V Gupta, JE Dick - Analytical chemistry, 2023 - ACS Publications
Here, we have developed and applied a triple-barrel microelectrode. This device
incorporates a platinum disk working electrode, a platinum disk counter electrode, and a low …

Developing a drug screening platform: MALDI-mass spectrometry imaging of paper-based cultures

F Tobias, JC McIntosh, GJ LaBonia, MW Boyce… - Analytical …, 2019 - ACS Publications
Many potential chemotherapeutics fail to reach patients. One of the key reasons is that
compounds are tested during the drug discovery stage in two-dimensional (2D) cell cultures …

Cellular invasion assay for the real-time tracking of individual cells in spheroid or tumor-like mimics

RM Kenney, MC Lee, MW Boyce, ZR Sitte… - Analytical …, 2023 - ACS Publications
Cellular invasion is the gateway to metastasis, with cells moving from a primary tumor into
neighboring regions of healthy tissue. Invasion assays provide a tractable experimental …