The 5-HT-related gut-brain axis in obesity

C Jiang, Q Zhan, C Zeng - Life Sciences, 2024 - Elsevier
Aims The incidence of obesity increases annually. It is closely related to the occurrence of
cardiovascular diseases, malignant tumors, etc., and has become a major global health …

Effects of Exercise on Gut Microbiota of Adults: A Systematic Review and Meta-Analysis

L Min, A Ablitip, R Wang, T Luciana, M Wei, X Ma - Nutrients, 2024 - mdpi.com
Background: The equilibrium between gut microbiota (GM) and the host plays a pivotal role
in maintaining overall health, influencing various physiological and metabolic functions …

Biomimetic nanoplatform with microbiome modulation and antioxidant functions ameliorating insulin resistance and pancreatic β-cell dysfunction for T2DM …

X Wang, R Tian, C Liang, Y Jia, L Zhao, Q Xie, F Huang… - Biomaterials, 2025 - Elsevier
Insulin resistance and pancreatic β-cell dysfunction are the main pathogenesis of type 2
diabetes mellitus (T2DM). However, insulin therapy and diabetes medications do not …

Sex-dependent effects of a high fat diet on metabolic disorders, intestinal barrier function and gut microbiota in mouse

C Lefebvre, A Tiffay, CE Breemeersch, V Dreux… - Scientific Reports, 2024 - nature.com
Obesity is often associated with sex-dependent metabolic complications, in which altered
intestinal barrier function and gut microbiota contribute. We aimed to characterize in mice …

Interactions between gut microbiota and natural bioactive polysaccharides in metabolic diseases

Y Pi, M Fang, Y Li, L Cai, R Han, W Sun, X Jiang… - Nutrients, 2024 - pmc.ncbi.nlm.nih.gov
The gut microbiota constitutes a complex ecosystem, comprising trillions of microbes that
have co-evolved with their host over hundreds of millions of years. Over the past decade, a …

[HTML][HTML] Probiotic, Postbiotic, and Paraprobiotic Effects of Lactobacillus rhamnosus as a Modulator of Obesity-Associated Factors

Obesity is a pandemic currently affecting the world's population that decreases the quality of
life and promotes the development of chronic non-communicable diseases. Lactobacillus …

Advancing lifelong precision medicine for cardiovascular diseases through gut microbiota modulation

B Shi, H Li, X He - Gut Microbes, 2024 - Taylor & Francis
The gut microbiome is known as the tenth system of the human body that plays a vital role in
the intersection between health and disease. The considerable inter-individual variability in …

Lacto-Fermented Fruits and Vegetables: Bioactive Components and Effects on Human Health

L Wei, W Van Beeck, M Hanlon… - Annual Review of …, 2025 - annualreviews.org
Lacto-fermented fruits and vegetables (FVs) such as kimchi, sauerkraut, and fermented
olives and nonalcoholic juices have a long history as dietary staples. Herein, the production …

[HTML][HTML] Epithelial metabolism as a rheostat for intestinal inflammation and malignancy

J Schwärzler, L Mayr, F Grabherr, H Tilg… - Trends in Cell Biology, 2024 - cell.com
The gut epithelium protects the host from a potentially hostile environment while allowing
nutrient uptake that is vital for the organism. To maintain this delicate task, the gut epithelium …

Glutamine metabolism improves left ventricular function but not macrophage-mediated inflammation following myocardial infarction

AJ Mouton, NM Aitken, JG Morato… - … of Physiology-Cell …, 2024 - journals.physiology.org
Glutamine is a critical amino acid that serves as an energy source, building block, and
signaling molecule for the heart tissue and the immune system. However, the role of …