The biological basis of consciousness is one of the most challenging and fundamental questions in 21st century science. A related pursuit aims to identify the neural correlates and …
Y Tu, Z Fu, F Zeng, N Maleki, L Lan, Z Li, J Park… - Neurology, 2019 - AAN Enterprises
Objective To investigate the dynamic functional connectivity of thalamocortical networks in interictal migraine patients and whether clinical features are associated with abnormal …
Background: Intraoperative burst-suppression is associated with postoperative delirium. Whether this association is causal remains unclear. Therefore, we investigated whether …
V Bonhomme, C Staquet, J Montupil… - Frontiers in Systems …, 2019 - frontiersin.org
General anesthesia reversibly alters consciousness, without shutting down the brain globally. Depending on the anesthetic agent and dose, it may produce different …
UC Lee, GA Mashour - Anesthesiology, 2018 - pmc.ncbi.nlm.nih.gov
The heterogeneity of molecular mechanisms, target neural circuits, and neurophysiological effects of general anesthetics makes it difficult to develop a reliable and drug-invariant index …
M Mahmoud, E Barbi, KP Mason - Journal of clinical medicine, 2020 - mdpi.com
Over the past few years, despite the lack of approved pediatric labelling, dexmedetomidine's (DEX) use has become more prevalent in pediatric clinical practice as well as in research …
State-dependent activity of locus ceruleus (LC) neurons has long suggested a role for noradrenergic modulation of arousal. However, in vivo insights into noradrenergic arousal …
SJT Van Montfort, E Van Dellen, CJ Stam… - NeuroImage: Clinical, 2019 - Elsevier
Delirium is an acute neuropsychiatric syndrome characterized by altered levels of attention and awareness with cognitive deficits. It is most prevalent in elderly hospitalized patients …
Recent studies have investigated local oscillations, long-range connectivity, and global network patterns to identify neural changes associated with anesthetic-induced …