Abstract Since its discovery 1, 2, 4-triazole ring has emerged as a prominent heterocyclic
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …

Microbes broadly constitute several organisms like viruses, protozoa, bacteria, and fungi
present in our biosphere. Fast-paced environmental changes have influenced contact of …

Rapidly growing antimicrobial resistance among clinically important bacterial and fungal
pathogens accounts for high morbidity and mortality worldwide. Therefore, it is critical to look …

Designing new synthetic strategies for indazoles is a prominent topic in contemporary
research. The transition-metal-catalyzed C–H activation/annulation sequence has arisen as …

Small-molecule probes are powerful tools for studying biological systems and can serve as
lead compounds for developing new therapeutics. Especially, nitrogen heterocycles are of …

In this study, a series of bis amide thiazolidine derivatives (Q1-Q6) were synthesized and
their anticancer activity was evaluated against prostate (PC3) and breast (MCF7) cancer …

N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of
these compounds, focusing on pioneering synthetic approaches, mechanistic insights and …

In this study, synthesis of 1, 2, 4 triazole-fluoroquinolone hybrid compounds was realized. 7a-
d hybrid compound was obtained as a result of mannich reaction with 6a-b triazole …

Arthropod-borne viruses (arboviruses) are a severe public health problem worldwide,
consisting of a significant part of all the emerging infectious diseases. It is estimated that …

A series of novel pentanediamide derivatives were designed, synthesized and evaluated as
S-adenosyl-l-homocysteine hydrolase (SAHase) inhibitors in this study. Some compounds …