Over 200 years ago, René Laennec published the first description of emphysema, an
important pathobiological element of what is today known as chronic obstructive pulmonary …

Background To date, no parameter with satisfactory accuracy exists for the diagnosis of
appendicitis. This retrospective study describes the discriminatory value of preoperative …

Background Eosinophils in peripheral blood are one of the emerging biomarkers in chronic
obstructive pulmonary disease (COPD) patients. However, when analysing the relationship …

The respiratory microbiome may influence the development and progression of COPD by
modulating local immune and inflammatory events. We aimed to investigate whether relative …

Purpose Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide, characterized by intense lung infiltrations of immune cells (macrophages and …

Cardiovascular diseases (CVDs) are the most common comorbidities in the chronic
obstructive pulmonary disease (COPD), which increase the risk of hospitalization, length of …

Background We previously reported a Phase 1/2 randomized placebo-controlled trial of
systemic administration of bone marrow-derived allogeneic MSCs (remestemcel-L) in …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous entity with different
clinical phenotypes, such as asthma-COPD overlap (ACO). The aim of this retrospective …

Aims To evaluate the expressions of intracellular cytokines in CD4+ T lymphocytes and to
investigate the correlation between biomarker expressions and clinical and functional …

Background We aimed to investigate the association between red cell index (RCI) and the
severity of Chronic Obstructive Pulmonary Disease (COPD), and compare predictive value …