Extraction and application of keratin from natural resources: a review

CR Chilakamarry, S Mahmood, SNBM Saffe… - 3 Biotech, 2021 - Springer
Over recent years, keratin has gained great popularity due to its exceptional biocompatible
and biodegradable nature. It has shown promising results in various industries like poultry …

Types I and II keratin intermediate filaments

JT Jacob, PA Coulombe, R Kwan… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Keratins—types I and II—are the intermediate-filament-forming proteins expressed in
epithelial cells. They are encoded by 54 evolutionarily conserved genes (28 type I, 26 type …

Keratins in health and disease

DM Toivola, P Boor, C Alam, P Strnad - Current opinion in cell biology, 2015 - Elsevier
The cytoprotective keratins (K) compose the intermediate filaments of epithelial cells and
their inherited and spontaneous mutations give rise to keratinopathies. For example …

[HTML][HTML] Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders

M Ho, B Thompson, JN Fisk, DW Nebert, EA Bruford… - Human Genomics, 2022 - Springer
Intermediate filament (IntFil) genes arose during early metazoan evolution, to provide
mechanical support for plasma membranes contacting/interacting with other cells and the …

Human hair keratin and its-based biomaterials for biomedical applications

H Lee, K Noh, SC Lee, IK Kwon, DW Han… - Tissue Engineering and …, 2014 - Springer
Over the past few decades, naturally derived biomaterials have been extensively used in
tissue engineering and regenerative medicine owing to their biological function, structural …

Regulation of keratin network organization

F Loschke, K Seltmann, JE Bouameur… - Current opinion in cell …, 2015 - Elsevier
Keratins form the major intermediate filament cytoskeleton of epithelia and are assembled
from heterodimers of 28 type I and 26 type II keratins in cell-and differentiation-dependent …

[HTML][HTML] Keratin 14-dependent disulfides regulate epidermal homeostasis and barrier function via 14-3-3σ and YAP1

Y Guo, CJ Redmond, KA Leacock, MV Brovkina, S Ji… - Elife, 2020 - elifesciences.org
The intermediate filament protein keratin 14 (K14) provides vital structural support in basal
keratinocytes of epidermis. Recent studies evidenced a role for K14-dependent disulfide …

[HTML][HTML] Evolutionary origin of Hoxc13-dependent skin appendages in amphibians

M Carron, AP Sachslehner, MB Cicekdal… - Nature …, 2024 - nature.com
Cornified skin appendages, such as hair and nails, are major evolutionary innovations of
terrestrial vertebrates. Human hair and nails consist largely of special intermediate filament …

Convergent evolution of cysteine-rich keratins in hard skin appendages of terrestrial vertebrates

F Ehrlich, J Lachner, M Hermann… - Molecular Biology …, 2020 - academic.oup.com
Terrestrial vertebrates have evolved hard skin appendages, such as scales, claws, feathers,
and hair that play crucial roles in defense, predation, locomotion, and thermal insulation …

[HTML][HTML] Order and disorder in intermediate filament proteins

M Kornreich, R Avinery, E Malka-Gibor, A Laser-Azogui… - FEBS letters, 2015 - Elsevier
Intermediate filaments (IFs), important components of the cytoskeleton, provide a versatile,
tunable network of self-assembled proteins. IF proteins contain three distinct domains: an α …