The psychostimulants, d-amphetamine (d-AMP) and methylphenidate (MPH), are widely
used to treat attention-deficit hyperactivity disorder (ADHD) in both children and adults. The …

Background: Because of the amphetamines' abuse potential and capability of exacerbating
or inducing mood and psychotic disturbances, investigations of the behavioral effects of …

Previous studies from this laboratory have demonstrated that a variety of psychostimulant
drugs can improve the performance of rats trained in a 2-choice stimulus detection task in …

The effects of nicotine on sustained attention were tested in F344× BN male rats when they
were chronologically middle and old aged. The rats (n= 11) were trained in a two-choice …

Previous work has demonstrated that drugs increasing brain concentrations of acetylcholine
can enhance cognition in aging and brain-damaged organisms. The present study assessed …

Rationale Low doses of d-amphetamine may enhance learning, depending on the
conditions under which learning is studied. Objective The objective of this study is to …

Previous work in our laboratory demonstrated that galantamine, a cholinesterase inhibitor
and weak cholinergic agonist, facilitated classical trace eyeblink conditioning in healthy …

Attention Deficit Hyperactivity Disorder (ADHD) is a common childhood psychiatric disorder
that often persists into adolescence and adulthood (Cherkasova, Ponde, & Hechtman, In …

Converging evidence suggests a dysfunction in dopamine (DA) neurotransmission in
attention deficit/hyperactivity disorder (ADHD). For example, DA genes are implicated in the …

Although drug misuse in people above middle age is not unusual, relatively little is known
about the effects of this on their brain and the consequences as they age. Cognitive function …