Electroencephalogram in the intensive care unit: a focused look at acute brain injury

A Alkhachroum, B Appavu, S Egawa, B Foreman… - Intensive care …, 2022 - Springer
Over the past decades, electroencephalography (EEG) has become a widely applied and
highly sophisticated brain monitoring tool in a variety of intensive care unit (ICU) settings …

Management of status epilepticus, refractory status epilepticus, and super-refractory status epilepticus

E Trinka, M Leitinger - CONTINUUM: Lifelong Learning in …, 2022 - journals.lww.com
PURPOSE OF REVIEW Status epilepticus is a serious condition caused by disorders and
diseases that affect the central nervous system. In status epilepticus, hypersynchronous …

Neurological toxicities associated with chimeric antigen receptor T-cell therapy

DB Rubin, HH Danish, AB Ali, K Li, S LaRose… - Brain, 2019 - academic.oup.com
Chimeric antigen receptor T cell therapy has become an important tool in the treatment of
relapsed and refractory malignancy; however, it is associated with significant neurological …

[HTML][HTML] The curing coma campaign: framing initial scientific challenges—proceedings of the first curing coma campaign scientific advisory council meeting

JJ Provencio, JC Hemphill, J Claassen, BL Edlow… - Neurocritical care, 2020 - Springer
Coma and disordered consciousness are common manifestations of acute neurological
conditions and are among the most pervasive and challenging aspects of treatment in …

[HTML][HTML] Metabolic reprogramming mediates hippocampal microglial M1 polarization in response to surgical trauma causing perioperative neurocognitive disorders

G Luo, X Wang, Y Cui, Y Cao, Z Zhao… - Journal of …, 2021 - Springer
Background Microglial polarization toward pro-inflammatory M1 phenotype are major
contributors to the development of perioperative neurocognitive disorders (PNDs). Metabolic …

Electroencephalographic periodic discharges and frequency-dependent brain tissue hypoxia in acute brain injury

J Witsch, HP Frey, JM Schmidt, A Velazquez… - JAMA …, 2017 - jamanetwork.com
Importance Periodic discharges (PDs) that do not meet seizure criteria, also termed theictal
interictal continuum, are pervasive on electroencephalographic (EEG) recordings after acute …

Continuous electroencephalography predicts delayed cerebral ischemia after subarachnoid hemorrhage: a prospective study of diagnostic accuracy

ES Rosenthal, S Biswal, SF Zafar… - Annals of …, 2018 - Wiley Online Library
Objective Delayed cerebral ischemia (DCI) is a common, disabling complication of
subarachnoid hemorrhage (SAH). Preventing DCI is a key focus of neurocritical care, but …

Time‐dependent risk of seizures in critically ill patients on continuous electroencephalogram

AF Struck, G Osman, N Rampal, S Biswal… - Annals of …, 2017 - Wiley Online Library
Objective Find the optimal continuous electroencephalographic (CEEG) monitoring duration
for seizure detection in critically ill patients. Methods We analyzed prospective data from 665 …

Continuous electroencephalography after moderate to severe traumatic brain injury

H Lee, MA Mizrahi, JA Hartings, S Sharma… - Critical care …, 2019 - journals.lww.com
Objectives: After traumatic brain injury, continuous electroencephalography is widely used to
detect electrographic seizures. With the development of standardized continuous …

Automated annotation of epileptiform burden and its association with outcomes

SF Zafar, ES Rosenthal, J Jing, W Ge… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to determine the dose–response relation between
epileptiform activity burden and outcomes in acutely ill patients. Methods A single center …