Dopamine, behavior, and addiction

RA Wise, CJ Jordan - Journal of biomedical science, 2021 - Springer
Addictive drugs are habit-forming. Addiction is a learned behavior; repeated exposure to
addictive drugs can stamp in learning. Dopamine-depleted or dopamine-deleted animals …

Mechanisms of the psychostimulant effects of caffeine: implications for substance use disorders

S Ferré - Psychopharmacology, 2016 - Springer
Background The psychostimulant properties of caffeine are reviewed and compared with
those of prototypical psychostimulants able to cause substance use disorders (SUD) …

An update on the mechanisms of the psychostimulant effects of caffeine

S Ferré - Journal of neurochemistry, 2008 - Wiley Online Library
There has been a long debate about the predominant involvement of the different adenosine
receptor subtypes and the preferential role of pre‐versus post‐synaptic mechanisms in the …

[PDF][PDF] Adenosine A1-A2A receptor heteromers: new targets for caffeine in the brain

S Ferre, F Ciruela, J Borycz, M Solinas, D Quarta… - Front Biosci, 2008 - researchgate.net
[Frontiers in Bioscience 13, 2391-2399, January 1, 2008] 2391 Adenosine A1-A2A receptor
heteromers: new targets for caffeine in Page 1 [Frontiers in Bioscience 13, 2391-2399, January …

Caffeine, a common active adulterant of cocaine, enhances the reinforcing effect of cocaine and its motivational value

JP Prieto, C Scorza, GP Serra, V Perra, M Galvalisi… - …, 2016 - Springer
Rationale Caffeine is one of the psychoactive substances most widely used as an adulterant
in illicit drugs, such as cocaine. Animal studies have demonstrated that caffeine is able to …

Body weight gain in rats consuming sweetened liquids. Effects of caffeine and diet composition

SE Swithers, AA Martin, KM Clark, AF Laboy… - Appetite, 2010 - Elsevier
Previous studies show that high-intensity sweeteners can stimulate weight gain in rats. The
present studies examined whether caffeine, a stimulant commonly added to beverages …

Conditioned reinforcement and locomotor activating effects of caffeine and ethanol combinations in mice

MLT Hilbert, CE May, WC Griffin III - Pharmacology Biochemistry and …, 2013 - Elsevier
A growing trend among ethanol drinkers, especially young adults, is to combine caffeinated
energy drinks with ethanol during a drinking episode. The primary active ingredient of these …

Periodical reactivation under the effect of caffeine attenuates fear memory expression in rats

LK Pedraza, RO Sierra, FN Lotz… - Scientific Reports, 2018 - nature.com
In the last decade, several studies have shown that fear memories can be attenuated by
interfering with reconsolidation. However, most of the pharmacological agents used in …

Caffeine increases the motivation to obtain non-drug reinforcers in rats

AB Sheppard, SC Gross, SA Pavelka, MJ Hall… - Drug and alcohol …, 2012 - Elsevier
Background: Caffeine is widely considered to be a reinforcer in humans, but this effect is
difficult to measure in non-human animals. We hypothesized that caffeine may have dual …

Cocaine-, caffeine-, and stress-evoked cocaine reinstatement in high vs. low impulsive rats: treatment with allopregnanolone

PS Regier, AB Claxton, NE Zlebnik… - Drug and alcohol …, 2014 - Elsevier
Background Previous research indicates that individual differences in traits such as
impulsivity, avidity for sweets, and novelty reactivity are predictors of several aspects of drug …