Silver nanoparticles (AgNPs) have become one of the most popular objects of study for the
past few decades. The ability to design AgNPs through different synthetic methods …

The lipid composition of cellular organelles is tailored to suit their specialized tasks. A
fundamental transition in the lipid landscape divides the secretory pathway in early and late …

The unfolded protein response (UPR) is a conserved homeostatic program that is activated
by misfolded proteins in the lumen of the endoplasmic reticulum (ER). Recently, it became …

Abstract TOR (T arget O f R apamycin) is a highly conserved protein kinase that is important
in both fundamental and clinical biology. In fundamental biology, TOR is a nutrient-sensitive …

Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …

Ceramides are a heterogeneous group of bioactive membrane sphingolipids that play
specialized regulatory roles in cellular metabolism depending on their characteristic fatty …

Sustainability of the environment has become pivotal in the modern world, and there have
been enormous efforts by the world leaders and organizations to reduce the effects of …

During the last decades, lipids have gained much attention due to their involvement in
health and disease. Lipids are required for the formation of membranes and contribute to …

Sphingolipids are essential lipids in eukaryotic membranes. In humans, the first and rate-
limiting step of sphingolipid synthesis is catalyzed by the serine palmitoyltransferase …

Protein folding homeostasis in the lumen of the endoplasmic reticulum is defended by signal
transduction pathways that are activated by an imbalance between unfolded proteins and …