Tumor cell infiltration into the brain in glioblastoma: from mechanisms to clinical perspectives
Simple Summary The estimated survival time for glioblastoma patients is extremely low; only
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
about 5% of patients survive five years post diagnosis. The standard of care for glioblastoma …
Cancer-associated fibroblasts: mechanisms of tumor progression and novel therapeutic targets
RP Czekay, DJ Cheon, R Samarakoon, SM Kutz… - Cancers, 2022 - mdpi.com
Simple Summary The tumor microenvironment plays an important role in determining the
biological behavior of several of the more aggressive malignancies. Among the various cell …
biological behavior of several of the more aggressive malignancies. Among the various cell …
SERPINE1 overexpression promotes malignant progression and poor prognosis of gastric cancer
S Chen, Y Li, Y Zhu, J Fei, L Song, G Sun… - Journal of …, 2022 - Wiley Online Library
The serine protease inhibitor clade E member 1 (SERPINE1) is a major inhibitor of tissue
plasminogen activator and urokinase, and has been implicated in the development and …
plasminogen activator and urokinase, and has been implicated in the development and …
A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma
M Khan, J Lin, B Wang, C Chen, Z Huang… - Frontiers in …, 2022 - frontiersin.org
Background Gastric cancer (GC) represents a major global clinical problem with very limited
therapeutic options and poor prognosis. Necroptosis, a recently discovered inflammatory …
therapeutic options and poor prognosis. Necroptosis, a recently discovered inflammatory …
Perampanel in brain tumor-related epilepsy: a systematic review
Brain tumor-related epilepsy (BTRE) is a common comorbidity in patients with brain
neoplasms and it may be either the first symptom or develop after the tumor diagnosis …
neoplasms and it may be either the first symptom or develop after the tumor diagnosis …
Data mining combines bioinformatics discover immunoinfiltration-related gene SERPINE1 as a biomarker for diagnosis and prognosis of stomach adenocarcinoma
Y Zhai, X Liu, Z Huang, J Zhang, A Stalin, Y Tan… - Scientific Reports, 2023 - nature.com
Stomach adenocarcinoma (STAD) is a type of cancer which often at itsadvanced stage apon
diagnosis and mortality in clinical practice. Several factors influencethe prognosis of STAD …
diagnosis and mortality in clinical practice. Several factors influencethe prognosis of STAD …
Immune-Related Gene SERPINE1 Is a Novel Biomarker for Diffuse Lower-Grade Gliomas via Large-Scale Analysis
X Huang, F Zhang, D He, X Ji, J Gao, W Liu… - Frontiers in …, 2021 - frontiersin.org
Background Glioma is one of the highly fatal primary tumors in the central nervous system.
As a major component of tumor microenvironment (TME), immune cell has been proved to …
As a major component of tumor microenvironment (TME), immune cell has been proved to …
[HTML][HTML] Anti‑tumor effects of perampanel in malignant glioma cells
J Tatsuoka, E Sano, Y Hanashima… - Oncology …, 2022 - spandidos-publications.com
Glioblastoma has a poor prognosis even after multimodal treatment, such as surgery,
chemotherapy and radiation therapy. Patients with glioblastoma frequently develop epileptic …
chemotherapy and radiation therapy. Patients with glioblastoma frequently develop epileptic …
Crosstalk between YAP and TGFβ regulates SERPINE1 expression in mesenchymal lung cancer cells
HJ Kong, EJ Kwon, OS Kwon… - International …, 2020 - spandidos-publications.com
Serpin family E member 1 (SERPINE1), a serine proteinase inhibitor, serves as an important
regulator of extra-cellular matrix remodeling. Emerging evidence suggests that SERPINE1 …
regulator of extra-cellular matrix remodeling. Emerging evidence suggests that SERPINE1 …
Bioinformatic analysis identifies key transcriptome signatures in temporal lobe epilepsy
QL Chen, L Xia, SP Zhong, Q Wang… - CNS neuroscience & …, 2020 - Wiley Online Library
Aims To identify transcriptome signatures underlying epileptogenesis in temporal lobe
epilepsy (TLE). Methods Robust rank aggregation analysis was used to integrate multiple …
epilepsy (TLE). Methods Robust rank aggregation analysis was used to integrate multiple …