The complement system is a recognized pillar of host defence against infection and noxious
self-derived antigens. Complement is traditionally known as a serum-effective system …

The recognition of microbial or danger-associated molecular patterns by complement
proteins initiates a cascade of events that culminates in the activation of surface complement …

The complement system has been considered for a long time as a simple lytic cascade,
aimed to kill bacteria infecting the host organism. Nowadays, this vision has changed and it …

As a preformed defense system, complement faces a delicate challenge in providing an
immediate, forceful response to pathogens even at first encounter, while sparing host cells in …

INTRODUCTION The inflammasomes and the complement system are traditionally viewed
as quintessential components of innate immunity required for the detection and elimination …

While red blood cell (RBC) transfusion is the most common medical intervention in
hospitalized patients, as with any therapeutic, it is not without risk. Allogeneic RBC exposure …

Complement is viewed as a critical serum-operative component of innate immunity, with
processing of its key component, C3, into activation fragments C3a and C3b confined to the …

Complement is traditionally known to be a system of serum proteins that provide protection
against pathogens through direct cell lysis and the mobilization of innate and adaptive …

The immune system is now considered a major factor in Alzheimer Disease (AD). This
review seeks to demonstrate how various aspects of the immune system, both in the brain …

The complement system is an evolutionarily ancient key component of innate immunity
required for the detection and removal of invading pathogens. It was discovered more than …