Autoimmune pre-disease

K Bieber, JE Hundt, X Yu, M Ehlers, F Petersen… - Autoimmunity …, 2023 - Elsevier
Approximately 5% of the world-wide population is affected by autoimmune diseases.
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …

Unmet medical needs in chronic, non-communicable inflammatory skin diseases

H Ujiie, D Rosmarin, MP Schön, S Ständer… - Frontiers in …, 2022 - frontiersin.org
An estimated 20–25% of the population is affected by chronic, non-communicable
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …

Treatment of pemphigus vulgaris and foliaceus with efgartigimod, a neonatal Fc receptor inhibitor: a phase II multicentre, open‐label feasibility trial

M Goebeler, Z Bata‐Csörgő… - British Journal of …, 2022 - academic.oup.com
Background Pemphigus vulgaris and pemphigus foliaceus are potentially life‐threatening
autoimmune disorders triggered by IgG autoantibodies against mucosal and epidermal …

S2k guidelines on the management of paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome initiated by the European Academy of …

E Antiga, R Bech, R Maglie, G Genovese… - Journal of the …, 2023 - Wiley Online Library
Background Paraneoplastic pemphigus (PNP), also called paraneoplastic autoimmune
multiorgan syndrome (PAMS), is a rare autoimmune disease with mucocutaneous and multi …

Autoimmune bullous dermatoses

MM Holtsche, K Boch, E Schmidt - JDDG: Journal der …, 2023 - Wiley Online Library
Autoimmune bullous dermatoses (AIBD) are a heterogeneous group of about a dozen
diseases characterized clinically by erosions and blisters and immunopathologically by …

Pemphigus‐und Pemphigoid‐Erkrankungen: Klinik, Diagnostik und Therapie: Pemphigus and pemphigoids: Clinical presentation, diagnosis and therapy

D Didona, MF Schmidt, R Maglie… - JDDG: Journal der …, 2023 - Wiley Online Library
Pemphigus und Pemphigoid sind seltene Autoimmunkrankheiten der Haut mit potenziell
lebensbedrohlichem Verlauf. Autoantikörper gegen epidermale und junktionale …

The role of sex and gender in dermatology-from pathogenesis to clinical implications

F Lagacé, K D'Aguanno, C Prosty… - Journal of …, 2023 - journals.sagepub.com
Background Sex and gender have increasingly been recognized as significant risk factors
for many diseases, including dermatological conditions. Historically, sex and gender have …

HLA class II antigens in Croatian patients with pemphigus vulgaris and their correlation with anti-desmoglein antibodies

I Lakoš Jukić, M Mokos, B Marinović - Frontiers in Immunology, 2023 - frontiersin.org
Pemphigus vulgaris (PV) is an acquired autoimmune blistering disease characterized by the
production of autoantibodies targeting desmosomal cadherins, primarily desmoglein 1 and …

A global view of pemphigus: Geographical variations

RP Timóteo, YM Pessoa-Gonçalves… - Clinical Reviews in …, 2024 - Springer
Pemphigus, an autoimmune intraepidermal bullous disease group with roughly eight distinct
forms, includes pemphigus vulgaris (PV) and pemphigus foliaceus (PF) as its predominant …

Effect of FcRn antagonism on protective antibodies and to vaccines in IgG-mediated autoimmune diseases pemphigus and generalised myasthenia gravis

JT Guptill, JW Sleasman, S Steeland, M Sips… - …, 2022 - Taylor & Francis
Antagonism of the neonatal Fc receptor (FcRn) by efgartigimod has been studied in several
autoimmune diseases mediated by immunoglobulin G (IgG) as a therapeutic approach to …