Browsing the oldest antioxidant enzyme: catalase and its multiple regulation in cancer

M Galasso, S Gambino, MG Romanelli… - Free Radical Biology …, 2021 - Elsevier
Aerobic organisms possess numerous antioxidant enzymatic families, including catalases,
superoxide dismutases (SODs), peroxiredoxins (PRDXs), and glutathione peroxidases …

Normalization methods for the analysis of unbalanced transcriptome data: a review

X Liu, N Li, S Liu, J Wang, N Zhang, X Zheng… - … in bioengineering and …, 2019 - frontiersin.org
Dozens of normalization methods for correcting experimental variation and bias in high-
throughput expression data have been developed during the last two decades. Up to 23 …

Digital droplet PCR in hematologic malignancies: a new useful molecular tool

S Galimberti, S Balducci, F Guerrini, M Del Re… - Diagnostics, 2022 - mdpi.com
Digital droplet PCR (ddPCR) is a recent version of quantitative PCR (QT-PCR), useful for
measuring gene expression, doing clonality assays and detecting hot spot mutations. In …

Pathogenic roles of S100A8 and S100A9 proteins in acute myeloid and lymphoid leukemia: clinical and therapeutic impacts

J Mondet, S Chevalier, P Mossuz - Molecules, 2021 - mdpi.com
Deregulations of the expression of the S100A8 and S100A9 genes and/or proteins, as well
as changes in their plasma levels or their levels of secretion in the bone marrow …

Digital PCR: a reliable tool for analyzing and monitoring hematologic malignancies

N Coccaro, G Tota, L Anelli, A Zagaria… - International journal of …, 2020 - mdpi.com
The digital polymerase chain reaction (dPCR) is considered to be the third-generation
polymerase chain reaction (PCR), as it yields direct, absolute and precise measures of …

Not only mutations matter: molecular picture of acute myeloid leukemia emerging from transcriptome studies

L Handschuh - Journal of oncology, 2019 - Wiley Online Library
The last two decades of genome‐scale research revealed a complex molecular picture of
acute myeloid leukemia (AML). On the one hand, a number of mutations were discovered …

Azacitidine is synergistically lethal with XPO1 inhibitor selinexor in acute myeloid leukemia by targeting XPO1/eIF4E/c-MYC signaling

H Long, Y Hou, J Li, C Song, Z Ge - International journal of molecular …, 2023 - mdpi.com
Acute myeloid leukemia (AML) is a high-mortality malignancy with poor outcomes.
Azacitidine induces cell death and demonstrates treatment effectiveness against AML …

A novel method based on a Mask R-CNN model for processing dPCR images

Z Hu, W Fang, T Gou, W Wu, J Hu, S Zhou, Y Mu - Analytical Methods, 2019 - pubs.rsc.org
A digital polymerase chain reaction (dPCR) using fluorescence images for collecting
quantitative information needs efficient software tools to automate the image analysis …

lncRNA SNHG3 facilitates acute myeloid leukemia cell growth via the regulation of miR‐758‐3p/SRGN axis

L Peng, Y Zhang, H Xin - Journal of cellular biochemistry, 2020 - Wiley Online Library
Small nucleolar RNA host gene 3 (SNHG3) is a newly identified long non‐coding RNA
whose dysregulation has been reported in several cancers. However, the details about …

Identification of an immune-related gene signature based on immunogenomic landscape analysis to predict the prognosis of adult acute myeloid leukemia patients

R Zhu, H Tao, W Lin, L Tang, Y Hu - Frontiers in Oncology, 2020 - frontiersin.org
Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by highly
heterogeneous molecular lesions and cytogenetic abnormalities. Immune disorders in AML …