The aim of this critical review is to provide a broad but digestible overview of
mechanochemical synthesis, ie reactions conducted by grinding solid reactants together …

The preparation of co-crystals via mechanochemistry combines the quest for clean and
green processes with the investigation of multicomponent new materials, among the …

Cocrystals have gained much interest in recent years owing to their potential to improve the
physicochemical properties of the parent compounds. It was once thought that cocrystals …

Polymorphism − A Perspective | Crystal Growth & Design ACS ACS Publications C&EN CAS
Find my institution Log In Crystal Growth & Design ACS Publications. Most Trusted. Most Cited …

Introduction: Cocrystallization is an effective crystal engineering approach for modifying the
crystal structure and properties of drugs. The number of examples of solving drug …

Pressing solid barbituric acid with KBr to prepare samples for IR spectroscopy leads to the
formation of an ionic co-crystal, in which the co-former is a classical ionic salt; co-crystal …

Engineering crystal properties by a choice of adequate molecular building blocks has to
cope with the fact that a given molecule can be isolated in many, at times very many, solid …

Isoniazid (INH) is a key drug ingredient in the fixed dose combination for the treatment of
tuberculosis (TB). INH is highly soluble in aqueous medium and also stable in pure form, but …

A 1: 1 cocrystal involving an analgesic drug, ethenzamide (EA), and 3, 5-dinitrobenzoic acid
exists in two polymorphs and forms a series of solvates. All the crystalline materials have …

Five new polymorphs and one hydrated form of 2‐thiobarbituric acid have been isolated and
characterised by solid‐state methods. In both the crystalline form II and in the hydrate form …