Abstract In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic
review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept …

For half a century, we have known that some patients experience neurocognitive dysfunction
after cardiac surgery, yet defining its incidence, course, and causes remains challenging …

Importance Delirium occurs in up to 52% of patients after cardiac surgery and may result
from changes in cerebral perfusion. Using intraoperative cerebral autoregulation monitoring …

The relationship between BP and downstream ischemia during hemodialysis has not been
characterized. We studied the dynamic relationship between BP, real-time symptoms, and …

Background Mean arterial pressure (MAP) below the lower limit of cerebral autoregulation
during cardiopulmonary bypass (CPB) is associated with complications after cardiac …

Objectives Optimizing blood pressure using near-infrared spectroscopy monitoring has been
suggested to ensure organ perfusion during cardiac surgery. Near-infrared spectroscopy is …

Background: Survivors of stroke often experience significant disability and impaired quality
of life. The recovery of motor or cognitive function requires long periods. Neuroimaging …

Injury to the central and peripheral nervous systems is often permanent. As such, adverse
neurological outcomes of surgery and anaesthesia can be devastating for patients and their …

The use of near-infrared spectroscopy (NIRS) has been increasingly adopted in cardiac
surgery to measure regional cerebral oxygen saturation. This method takes advantage of the …

Modern day cardiac surgery evolved upon the advent of cardiopulmonary bypass machines
(CPB) in the 1950s. Following this development, cardiac surgery in recent years has …