[HTML][HTML] Modern plant breeding techniques in crop improvement and genetic diversity: from molecular markers and gene editing to artificial intelligence—A critical …
With the development of new technologies in recent years, researchers have made
significant progress in crop breeding. Modern breeding differs from traditional breeding …
significant progress in crop breeding. Modern breeding differs from traditional breeding …
[HTML][HTML] Influence of genetic and cardiometabolic risk factors in Alzheimer's disease
G Pasqualetti, T Thayanandan, P Edison - Ageing research reviews, 2022 - Elsevier
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder. Cardiometabolic
and genetic risk factors play an important role in the trajectory of AD. Cardiometabolic risk …
and genetic risk factors play an important role in the trajectory of AD. Cardiometabolic risk …
Altered blood gene expression in the obesity-related type 2 diabetes cluster may be causally involved in lipid metabolism: a Mendelian randomisation study
Aims/hypothesis The aim of this study was to identify differentially expressed long non-
coding RNAs (lncRNAs) and mRNAs in whole blood of people with type 2 diabetes across …
coding RNAs (lncRNAs) and mRNAs in whole blood of people with type 2 diabetes across …
Disentangling the common genetic architecture and causality of rheumatoid arthritis and systemic lupus erythematosus with COVID‐19 outcomes: Genome‐wide …
Abstract Coronavirus Disease (COVID‐19) may cause a dysregulation of the immune
system and has complex relationships with multiple autoimmune diseases, including …
system and has complex relationships with multiple autoimmune diseases, including …
Genetic evidence for protective effects of angiotensin-converting enzyme against Alzheimer disease but not other neurodegenerative diseases in European …
Background and Objectives Angiotensin-converting enzyme (ACE) inhibitors are a
commonly prescribed class of medication used to treat heart failure, hypertension, and …
commonly prescribed class of medication used to treat heart failure, hypertension, and …
A multi-trait association analysis of brain disorders and platelet traits identifies novel susceptibility loci for major depression, Alzheimer's and Parkinson's disease
A Tirozzi, MS Quiccione, C Cerletti, MB Donati… - Cells, 2023 - mdpi.com
Among candidate neurodegenerative/neuropsychiatric risk-predictive biomarkers, platelet
count, mean platelet volume and platelet distribution width have been associated with the …
count, mean platelet volume and platelet distribution width have been associated with the …
Genome-wide cross-trait analysis and Mendelian randomization reveal a shared genetic etiology and causality between COVID-19 and venous thromboembolism
Venous thromboembolism occurs in up to one-third of patients with COVID-19. Venous
thromboembolism and COVID-19 may share a common genetic architecture, which has not …
thromboembolism and COVID-19 may share a common genetic architecture, which has not …
A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores
Background More than 75 common variant loci account for only a portion of the heritability
for Alzheimer's disease (AD). A more complete understanding of the genetic basis of AD can …
for Alzheimer's disease (AD). A more complete understanding of the genetic basis of AD can …
Exome-wide association study identified clusters of pleiotropic genetic associations with Alzheimer's disease and thirteen cardiovascular traits
Y Loika, E Loiko, I Culminskaya, AM Kulminski - Genes, 2023 - mdpi.com
Alzheimer's disease (AD) and cardiovascular traits might share underlying causes. We
sought to identify clusters of cardiovascular traits that share genetic factors with AD. We …
sought to identify clusters of cardiovascular traits that share genetic factors with AD. We …
Neuroprotection and axon regeneration by novel low-molecular-weight compounds through the modification of DOCK3 conformation
K Namekata, N Tsuji, X Guo, E Nishijima… - Cell Death …, 2023 - nature.com
Abstract Dedicator of cytokinesis 3 (DOCK3) is an atypical member of the guanine
nucleotide exchange factors (GEFs) and plays important roles in neurite outgrowth. DOCK3 …
nucleotide exchange factors (GEFs) and plays important roles in neurite outgrowth. DOCK3 …