Opportunities for histone deacetylase inhibition in amyotrophic lateral sclerosis
YE Klingl, D Pakravan… - British Journal of …, 2021 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease. ALS
patients suffer from a progressive loss of motor neurons, leading to respiratory failure within …
patients suffer from a progressive loss of motor neurons, leading to respiratory failure within …
Minimally invasive quantification of cerebral P2X7R occupancy using dynamic [18F]JNJ-64413739 PET and MRA-driven image derived input function
N Mertens, ME Schmidt, A Hijzen… - Scientific Reports, 2021 - nature.com
Abstract [18F] JNJ-64413739 has been evaluated as PET-ligand for in vivo quantification of
purinergic receptor subtype 7 receptor (P2X7R) using Logan graphical analysis with a …
purinergic receptor subtype 7 receptor (P2X7R) using Logan graphical analysis with a …
[HTML][HTML] Discovery of Novel Inhibitors against ALS-Related SOD1 (A4V) Aggregation through the Screening of a Chemical Library Using Differential Scanning …
M Giannakou, I Akrani, A Tsoka… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Cu/Zn Superoxide Dismutase 1 (SOD1) is a 32 kDa cytosolic dimeric
metalloenzyme that neutralizes superoxide anions into oxygen and hydrogen peroxide …
metalloenzyme that neutralizes superoxide anions into oxygen and hydrogen peroxide …
Discovery and characterization of novel inhibitors against ALS-related SOD1 (A4V) aggregation through screening of a chemical library using Differerential Scanning …
M Giannakou, C Vorgias, DG Hatzinikolaou - bioRxiv, 2023 - biorxiv.org
ABSTRACT Cu/Zn Superoxide Dismutase 1 (SOD1) is a 32-kDa cytosolic dimeric
metalloenzyme that neutralizes superoxide anions into harmless oxygen and hydrogen …
metalloenzyme that neutralizes superoxide anions into harmless oxygen and hydrogen …