[HTML][HTML] Cell polarity signaling in the plasticity of cancer cell invasiveness
A Gandalovičová, T Vomastek, D Rosel, J Brábek - Oncotarget, 2016 - ncbi.nlm.nih.gov
Apico-basal polarity is typical of cells present in differentiated epithelium while front-rear
polarity develops in motile cells. In cancer development, the transition from epithelial to …
polarity develops in motile cells. In cancer development, the transition from epithelial to …
The effectiveness of blood-activating and stasis-transforming traditional Chinese medicines (BAST) in lung cancer progression-a comprehensive review
S Wu, Z Sun, Z Guo, P Li, Q Mao, Y Tang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Blood-activating and stasis-transforming traditional
Chinese medicines (BAST) are a class of herbs that have the effect of dilating blood vessels …
Chinese medicines (BAST) are a class of herbs that have the effect of dilating blood vessels …
[HTML][HTML] Inhibition of oxidative stress-induced epithelial-mesenchymal transition in retinal pigment epithelial cells of age-related macular degeneration model by …
YC Yang, Y Chien, AA Yarmishyn, LY Lim… - Journal of Advanced …, 2024 - Elsevier
Introduction Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE)
cells is related to the pathogenesis of various retinopathies including age-related macular …
cells is related to the pathogenesis of various retinopathies including age-related macular …
EGF augments TGFβ-induced epithelial–mesenchymal transition by promoting SHP2 binding to GAB1
JM Buonato, IS Lan, MJ Lazzara - Journal of cell science, 2015 - journals.biologists.com
In many epithelial cells, epidermal growth factor (EGF) augments the epithelial–
mesenchymal transition (EMT) that occurs when cells are treated with transforming growth …
mesenchymal transition (EMT) that occurs when cells are treated with transforming growth …
Prostaglandin E2 promotes hepatocellular carcinoma cell invasion through upregulation of YB-1 protein expression
H Zhang, S Cheng, M Zhang, X Ma… - International …, 2013 - spandidos-publications.com
Prostaglandin E2 (PGE2) has been implicated in hepatocellular carcinoma cell invasion.
Recently, it was reported that Y box-binding protein 1 (YB-1) is closely correlated with …
Recently, it was reported that Y box-binding protein 1 (YB-1) is closely correlated with …
Baicalein inhibits fibronectin-induced epithelial–mesenchymal transition by decreasing activation and upregulation of calpain-2
Y Chen, L Chen, D Hong, Z Chen, J Zhang, L Fu… - Cell Death & …, 2019 - nature.com
The extracellular matrix protein fibronectin (FN) facilitates tumorigenesis and the
development of breast cancer. Inhibition of the FN-induced cellular response is a potential …
development of breast cancer. Inhibition of the FN-induced cellular response is a potential …
[HTML][HTML] Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of …
Y Wu, JL Meitzler, S Antony, A Juhasz, J Lu, G Jiang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Several NADPH oxidase family members, including dual oxidase 2 [DUOX2], are expressed
in human tumors, particularly gastrointestinal cancers associated with long-standing chronic …
in human tumors, particularly gastrointestinal cancers associated with long-standing chronic …
Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner
The 90 kDa ribosomal S6 kinases (RSK) are effectors of the Ras-ERK1/2 signaling pathway.
RSK signaling controls proliferation and protein synthesis, and is altered in several types of …
RSK signaling controls proliferation and protein synthesis, and is altered in several types of …
Targeted inhibition of MEK1 by cobimetinib leads to differentiation and apoptosis in neuroblastoma cells
A Singh, Y Ruan, T Tippett, A Narendran - Journal of Experimental & …, 2015 - Springer
Background Neuroblastoma (NB) is one of the most common childhood malignancies.
Currently, high risk NB carries a poor outcome and significant treatment related toxicities …
Currently, high risk NB carries a poor outcome and significant treatment related toxicities …
Characterization of RACK1-depleted mammalian cells by a palette of microscopy approaches reveals defects in cell cycle progression and polarity establishment
V Chvalova, V Venkadasubramanian, Z Klimova… - Experimental Cell …, 2023 - Elsevier
Abstract The Receptor for Activated C Kinase 1 (RACK1) is an evolutionarily conserved
scaffold protein involved in the regulation of numerous cellular processes. Here, we used …
scaffold protein involved in the regulation of numerous cellular processes. Here, we used …