Exploring potential Plasmodium kinase inhibitors: a combined docking, MD and QSAR studies
SG Kankinou, M Yildiz, A Kocak - Journal of Biomolecular …, 2024 - Taylor & Francis
Malaria is a disease caused mostly by Plasmodium falciparum, affects millions of people
each year. The kinases are validated targets for malaria infection. In this study, we …
each year. The kinases are validated targets for malaria infection. In this study, we …
Insights into the Mechanism of Catalytic Activity of Plasmodium Parasite Malate-Quinone Oxidoreductase
T Ito, Y Tojo, M Fujii, K Nishino, H Kosako… - ACS …, 2024 - ACS Publications
Plasmodium malate-quinone oxidoreductase (MQO) is a membrane flavoprotein catalyzing
the oxidation of malate to oxaloacetate and the reduction of quinone to quinol. Recently …
the oxidation of malate to oxaloacetate and the reduction of quinone to quinol. Recently …
Dihydrostilbenes from Macaranga javanica (Blume) Müll. Arg. and their antiplasmodial activity
TS Tjahjandarie, MF Aldin, RD Saputri… - Natural Product …, 2024 - Taylor & Francis
An undescribed dihydrostilbene, macajavanicin D (1), and three known analogs,
malayheyneiin A (2) and laevifolins AB (3-4), were isolated from Macaranga javanica …
malayheyneiin A (2) and laevifolins AB (3-4), were isolated from Macaranga javanica …
Three new dihydrochalcones from the leaves of Artocarpus sericicarpus Jarrett and their activity against Plasmodium falciparum
Three new dihydrochalcones: artoserichalcone AC (1-3), were isolated from the leaves of
Artocarpus sericicarpus. The structures of compounds were determined based on NMR …
Artocarpus sericicarpus. The structures of compounds were determined based on NMR …
Effects of Ellagic Acid on Hemoglobin Ingestion, Transport, and Digestion in the Digestive Vacuole of Plasmodium falciparum
AC Thuduhena, N Abu-Bakar… - Journal of Microscopy …, 2024 - journals.lww.com
Aim: This study aimed to elucidate the mechanism of ellagic acid antimalarial action against
3D7 and W2 strains of P. falciparum in vitro by using a transmission electron microscope …
3D7 and W2 strains of P. falciparum in vitro by using a transmission electron microscope …
Efficacy and mechanism of action of cipargamin as an antibabesial drug candidate
Babesiosis is a disease brought on by intraerythrocytic parasites of the genus Babesia.
Current chemotherapies are accompanied by side effects and parasite relapse. Therefore, it …
Current chemotherapies are accompanied by side effects and parasite relapse. Therefore, it …
Comparison of methyl isoeugenol and methyl eugenol as renewable starting reagents for the synthesis of thiourea compounds for anti-Plasmodium falciparum
Several thiourea derivative compounds have been used as inhibitors of Plasmodium
falciparum via the plasmepsin inhibition pathway. The thiourea derivative (compound 3) …
falciparum via the plasmepsin inhibition pathway. The thiourea derivative (compound 3) …