Pharmacology of medical cannabis
MR Amin, DW Ali - Recent advances in cannabinoid physiology and …, 2019 - Springer
The Cannabis plant has been used for many of years as a medicinal agent in the relief of
pain and seizures. It contains approximately 540 natural compounds including more than …
pain and seizures. It contains approximately 540 natural compounds including more than …
Endocannabinoid signaling and synaptic function
Endocannabinoids are key modulators of synaptic function. By activating cannabinoid
receptors expressed in the central nervous system, these lipid messengers can regulate …
receptors expressed in the central nervous system, these lipid messengers can regulate …
A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo
Endocannabinoids (eCBs) are retrograde neuromodulators with important functions in a
wide range of physiological processes, but their in vivo dynamics remain largely …
wide range of physiological processes, but their in vivo dynamics remain largely …
[HTML][HTML] Cannabinoids and epilepsy
Cannabis has been used for centuries to treat seizures. Recent anecdotal reports,
accumulating animal model data, and mechanistic insights have raised interest in cannabis …
accumulating animal model data, and mechanistic insights have raised interest in cannabis …
Cannabinoid receptors: An update on cell signaling, pathophysiological roles and therapeutic opportunities in neurological, cardiovascular, and inflammatory …
The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …
has been one of the most significant biochemical and pharmacological advancements to …
The molecular logic of endocannabinoid signalling
D Piomelli - Nature Reviews Neuroscience, 2003 - nature.com
The endocannabinoids are a family of lipid messengers that engage the cell surface
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …
Signalling cognition: the gut microbiota and hypothalamic-pituitary-adrenal axis
JA Rusch, BT Layden, LR Dugas - Frontiers in endocrinology, 2023 - frontiersin.org
Cognitive function in humans depends on the complex and interplay between multiple body
systems, including the hypothalamic-pituitary-adrenal (HPA) axis. The gut microbiota, which …
systems, including the hypothalamic-pituitary-adrenal (HPA) axis. The gut microbiota, which …
Metaplasticity: tuning synapses and networks for plasticity
WC Abraham - Nature Reviews Neuroscience, 2008 - nature.com
Synaptic plasticity is a key component of the learning machinery in the brain. It is vital that
such plasticity be tightly regulated so that it occurs to the proper extent at the proper time …
such plasticity be tightly regulated so that it occurs to the proper extent at the proper time …
Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes
M Navarrete, A Araque - Neuron, 2010 - cell.com
Endocannabinoids and their receptor CB1 play key roles in brain function. Astrocytes
express CB1Rs that are activated by endocannabinoids released by neurons. However, the …
express CB1Rs that are activated by endocannabinoids released by neurons. However, the …
The emerging role of the endocannabinoid system in endocrine regulation and energy balance
During the last few years, the endocannabinoid system has emerged as a highly relevant
topic in the scientific community. Many different regulatory actions have been attributed to …
topic in the scientific community. Many different regulatory actions have been attributed to …