Association of microRNAs and YRNAs with platelet function

D Kaudewitz, P Skroblin, LH Bender, T Barwari… - Circulation …, 2016 - Am Heart Assoc
Rationale: Platelets shed microRNAs (miRNAs). Plasma miRNAs change on platelet
inhibition. It is unclear whether plasma miRNA levels correlate with platelet function …

Prognostic value of circulating tumor cells and disseminated tumor cells in patients with ovarian cancer: a systematic review and meta-analysis

L Cui, J Kwong, CC Wang - Journal of ovarian research, 2015 - Springer
Recent studies have shown diagnostic and prognostic values of circulating tumor cells
(CTCs) and disseminated tumor cells (DTCs) in various cancers, including ovarian cancer …

Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells

TAP Driedonks, SG van der Grein, Y Ariyurek… - Cellular and Molecular …, 2018 - Springer
The release and uptake of nano-sized extracellular vesicles (EV) is a highly conserved
means of intercellular communication. The molecular composition of EV, and thereby their …

True gene silencing

M Nashimoto - International Journal of Molecular Sciences, 2022 - mdpi.com
TRUE gene silencing is an RNA-mediated gene expression control technology and is
termed after tRNase ZL-utilizing efficacious gene silencing. In this review, I overview the …

[HTML][HTML] Alternative miRNAs? Human sequences misidentified as plant miRNAs in plant studies and in human plasma

KW Witwer - F1000Research, 2018 - ncbi.nlm.nih.gov
Background: A 2017 study reported that “Plant miRNAs found in human circulating system
provide evidences of cross kingdom RNAi”. Analysis of two human blood plasma …

Investigation of the transability of dietary small non-coding RNAs to animals

M Norouzi, MR Bakhtiarizadeh, A Salehi - Frontiers in Genetics, 2022 - frontiersin.org
Our daily diet not only provides essential nutrients needed for survival and growth but also
supplies bioactive ingredients to promote health and prevent disease. Recent studies have …

Blocking abundant RNA transcripts by high-affinity oligonucleotides during transcriptome library preparation

C Everaert, J Verwilt, K Verniers, N Vandamme… - Biological Procedures …, 2023 - Springer
Background RNA sequencing has become the gold standard for transcriptome analysis but
has an inherent limitation of challenging quantification of low-abundant transcripts. In …

TRUE gene silencing: screening of a heptamer-type small guide RNA library for potential cancer therapeutic agents

A Haino, T Ishikawa, M Seki… - Journal of Visualized …, 2016 - pmc.ncbi.nlm.nih.gov
TRUE gene silencing (termed after tRNase ZL-utilizing efficacious gene silencing) is one of
the RNA-directed gene silencing technologies, which utilizes an artificial small guide RNA …

[HTML][HTML] The Y4-RNA fragment, a potential diagnostic marker, exists in saliva

T Ishikawa, A Haino, M Seki, H Terada… - Non-coding RNA …, 2017 - Elsevier
The 94-nt full-length Y4-RNA is thought to have roles in the initiation of DNA replication and
RNA quality control. Although its 31/32-nt fragment also exists abundantly in plasma, little is …

[HTML][HTML] Potential physiological roles of the 31/32-nucleotide Y4-RNA fragment in human plasma

S Ninomiya, T Ishikawa, M Takahashi, M Seki… - Non-coding RNA …, 2019 - Elsevier
Abstract The 31-and 32-nt 5′-fragments of Y4-RNA (Y4RNAfr) exist abundantly in human
plasma. The Y4RNAfr can function as 5′-half-tRNA-type sgRNA for tRNase ZL, although …