Biochemistry and pharmacology of proteins and peptides purified from the venoms of the snakes Macrovipera lebetina subspecies

J Siigur, A Aaspõllu, E Siigur - Toxicon, 2019 - Elsevier
The isolation and characterization of individual snake venom components is important for a
deeper understanding of the pathophysiology of envenomations, for improving the …

Venomics of the milos viper (Macrovipera schweizeri) unveils patterns of venom composition and exochemistry across blunt-nosed viper venoms

L Schulte, M Damm, I Avella, L Uhrig… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: Snakebite is a neglected tropical disease and a globally important driver of
death and morbidity. Vipers of the genus Macrovipera (Viperidae: Viperinae) are among the …

Vipers of the middle east: a rich source of bioactive molecules

M Rima, SM Alavi Naini, M Karam, R Sadek… - Molecules, 2018 - mdpi.com
Snake venom serves as a tool of defense against threat and helps in prey digestion. It
consists of a mixture of enzymes, such as phospholipase A2, metalloproteases, and l-amino …

Combined venom profiling and cytotoxicity screening of the Radde's mountain viper (Montivipera raddei) and Mount Bulgar Viper (Montivipera bulgardaghica) with …

A Nalbantsoy, BF Hempel, D Petras, P Heiss… - Toxicon, 2017 - Elsevier
Here we report the first characterization of the endemic Mount Bulgar Viper (Montivipera
bulgardaghica) and Radde's mountain viper (Montivipera raddei) venom by a combined …

Investigating the cytotoxic effects of the venom proteome of two species of the Viperidae family (Cerastes cerastes and Cryptelytrops purpureomaculatus) from various …

CS Ozverel, M Damm, BF Hempel, B Göçmen… - … and Physiology Part C …, 2019 - Elsevier
Animal secretions are of great interest in terms of drug development due to their complex
protein and peptide composition. Especially, in the field of therapeutic medications such as …

Antioxidant, cytotoxic and anti-inflammatory properties of Anthemis tricolor Boiss. through a series of cellular assays and inhibition of Turkish Macrovipera lebetina …

D Aşkın, TD Akbulut, S Baykan, B Göçmen… - İstanbul Journal of …, 2023 - dergipark.org.tr
Background and Aims: Venom of Macrovipera lebetina obtusa (Viperidae), Turkey's biggest
viper, is highly toxic to humans and causes inflammation. In Anatolian traditional medicine …

Morphometric characteristics and seasonal proximity to water of the Cypriot bluntnosed viper Macrovipera lebetina lebetina (Linnaeus, 1758)

D Jestrzemski, I Kuzyakova - Journal of Venomous Animals and …, 2019 - SciELO Brasil
Background: The blunt-nosed viper Macrovipera lebetina (Linnaeus, 1758) is a medically
important snake species in the Middle East. Its nominate subspecies Macrovipera l. lebetina …

Individual variation in Macrovipera lebetinus obtusa (blunt-nosed viper) venom from a limited area in Southeastern Anatolia (Türkiye)

R Gürbüz, Ş Eroğlu Oylum, T Apaydin, MZ Yıldız… - Toxin …, 2024 - Taylor & Francis
Intraspecific variation in snake venom composition has been the subject of many studies,
revealing the differences in venom proteomes according to age, diet, sex, and geographic …

[PDF][PDF] In Vitro Cytotoxic and Proapoptotic Activities of Anatolian Macrovipera Lebetina Obtusa (Dwigubski, 1832) Crude Venom on Cultured K562 Human Chronic …

F Suzergoz, N Igci, C Cavus, MZ Yildiz… - … of Hematology & …, 2016 - researchgate.net
In the context of searching for anticancer compounds in natural products, snake venom is
one of the important sources for peptide/protein based bioactive molecules. Proteins and …

[PDF][PDF] Cytotoxic potential of Wagner's Viper, Montivipera wagneri, venom.

A Nalbantsoy, N İĞCİ, B GÖÇMEN… - North-Western Journal …, 2016 - biozoojournals.ro
Snake venoms contain a variety of biologically active proteins, which have therapeutic
potential. Montivipera wagneri is an endemic mountain viper species of Turkey. In this study …