Circulating biomarkers in patients with glioblastoma

J Müller Bark, A Kulasinghe, B Chua, BW Day… - British journal of …, 2020 - nature.com
Gliomas are the most common tumours of the central nervous system and the most
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …

Detection methods and clinical applications of circulating tumor cells in breast cancer

H Zhang, X Lin, Y Huang, M Wang, C Cen… - Frontiers in …, 2021 - frontiersin.org
Circulating Tumor Cells (CTCs) are cancer cells that split away from the primary tumor and
appear in the circulatory system as singular units or clusters, which was first reported by Dr …

Cancer cell dormancy: mechanisms and implications of cancer recurrence and metastasis

X Gao, M Zhang, Y Tang, X Liang - OncoTargets and therapy, 2017 - Taylor & Francis
More recently, disease metastasis and relapse in many cancer patients several years (even
some decades) after surgical remission are regarded as tumor dormancy. However, the …

The prognostic significance of circulating tumor cells in head and neck and non‐small‐cell lung cancer

A Kulasinghe, J Kapeleris, R Kimberley… - Cancer …, 2018 - Wiley Online Library
Tumor biopsy is the gold standard for the assessment of clinical biomarkers for treatment.
However, tumors change dynamically in response to therapy, and there remains a need for …

Liquid biopsy in head and neck cancer: promises and challenges

T Nonaka, DTW Wong - Journal of dental research, 2018 - journals.sagepub.com
Head and neck cancer is the sixth most common cancer worldwide. It remains one of the
leading causes of death, and its early detection is crucial. Liquid biopsy has emerged as a …

Cancer stem cells in head and neck squamous cell carcinoma: identification, characterization and clinical implications

C Peitzsch, J Nathansen, SI Schniewind, F Schwarz… - Cancers, 2019 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth most commonly diagnosed
cancer worldwide. Despite advances in the treatment management, locally advanced …

The role of circulating biomarkers in lung cancer

S Herath, H Sadeghi Rad, P Radfar, R Ladwa… - Frontiers in …, 2022 - frontiersin.org
Lung cancer is the leading cause of cancer morbidity and mortality worldwide and early
diagnosis is crucial for the management and treatment of this disease. Non-invasive means …

Capture of circulating tumour cell clusters using straight microfluidic chips

A Kulasinghe, J Zhou, L Kenny, I Papautsky… - Cancers, 2019 - mdpi.com
Circulating tumour cells (CTCs) are the metastatic precursors to distant disease in head and
neck cancers (HNCs). Whilst the prognostic and predictive value of single CTCs have been …

Enrichment of circulating head and neck tumour cells using spiral microfluidic technology

A Kulasinghe, THP Tran, T Blick, K O'Byrne… - Scientific reports, 2017 - nature.com
Whilst locoregional control of head and neck cancers (HNCs) has improved over the last
four decades, long-term survival has remained largely unchanged. A possible reason for this …

Understanding the tumor microenvironment in head and neck squamous cell carcinoma

HS Rad, Y Shiravand, P Radfar… - Clinical & …, 2022 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) represents a heterogeneous group of
tumors. While significant progress has been made using multimodal treatment, the 5‐year …