Erythropoietin‐mediated tissue protection: reducing collateral damage from the primary injury response

M Brines, A Cerami - Journal of internal medicine, 2008 - Wiley Online Library
In its classic hormonal role, erythropoietin (EPO) is produced by the kidney and regulates
the number of erythrocytes within the circulation to provide adequate tissue oxygenation …

[HTML][HTML] The role of endogenous neuroprotective mechanisms in the prevention of retinal ganglion cells degeneration

M Pietrucha-Dutczak, M Amadio, S Govoni… - Frontiers in …, 2018 - frontiersin.org
Retinal neurons are not able to undergo spontaneous regeneration in response to damage.
A variety of stressors, ie, UV radiation, high temperature, ischemia, allergens, and others …

Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli

H Huang, M Constante, A Layoun… - Blood, The Journal of …, 2009 - ashpublications.org
Hepcidin, a key regulator of iron metabolism, is a small antimicrobial peptide produced by
the liver that regulates intestinal iron absorption and iron recycling by macrophages …

[HTML][HTML] Current evidence on the protective effects of recombinant human erythropoietin and its molecular variants against pathological hallmarks of Alzheimer's …

JJ Jarero-Basulto, MC Rivera-Cervantes… - Pharmaceuticals, 2020 - mdpi.com
Substantial evidence in the literature demonstrates the pleiotropic effects of the
administration of recombinant human erythropoietin (rhEPO) and its molecular variants in …

[HTML][HTML] Fibronectin potentiates topical erythropoietin-induced wound repair in diabetic mice

S Hamed, Y Ullmann, D Egozi, E Daod, E Hellou… - Journal of investigative …, 2011 - Elsevier
Diabetes mellitus disrupts all phases of the wound repair cascade and leads to development
of chronic wounds. We previously showed that topical erythropoietin (EPO) can promote …

[HTML][HTML] Virus-mediated EpoR76E gene therapy preserves vision in a glaucoma model by modulating neuroinflammation and decreasing oxidative stress

J Hines-Beard, WS Bond, JR Backstrom… - Journal of …, 2016 - Springer
Background Glaucoma is a complex neurodegeneration and a leading cause of blindness
worldwide. Current therapeutic strategies, which are all directed towards lowering the …

The nonhematopoietic effects of erythropoietin in skin regeneration and repair: from basic research to clinical use

H Sorg, Y Harder, C Krueger… - Medicinal research …, 2013 - Wiley Online Library
Erythropoietin (EPO) is the main regulator of red blood cell production but there exists also a
variety of nonhematopoietic properties. More recent data show that EPO is also associated …

[HTML][HTML] Midkine, a potential link between obesity and insulin resistance

N Fan, H Sun, Y Wang, L Zhang, Z Xia, L Peng, Y Hou… - PloS one, 2014 - journals.plos.org
Obesity is associated with increased production of inflammatory mediators in adipose tissue,
which contributes to chronic inflammation and insulin resistance. Midkine (MK) is a heparin …

Serum midkine level might be a diagnostic tool for COVID19 disease in pregnancy: From the disease severity, hospitalization and disease progression respects

N Yazihan, SA Erol, S Akdas, SG Ayhan, A Atalay… - Cytokine, 2022 - Elsevier
Background New biomarkers for diagnosis and monitoring the COVID-19 disease are the
most important topics to be studied recently. We aimed to investigate the association …

Роль кислородсвязывающих свойств крови в развитии окислительного стресса, индуцированного липополисахаридом

АН Глебов, ЕВ Шульга - 2011 - elibrary.ru
В данной монографии представлен анализ роли кислородсвязывающих свойств крови
в развитии окислительного стресса, индуцированного липополисахаридом. Показан …