Is oxytocin “nature's medicine”?

CS Carter, WM Kenkel, EL MacLean, SR Wilson… - Pharmacological …, 2020 - Elsevier
Oxytocin is a pleiotropic, peptide hormone with broad implications for general health,
adaptation, development, reproduction, and social behavior. Endogenous oxytocin and …

Inflammation: the link between comorbidities, genetics, and Alzheimer's disease

EA Newcombe, J Camats-Perna, ML Silva… - Journal of …, 2018 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder, most cases of which lack a clear
causative event. This has made the disease difficult to characterize and, thus, diagnose …

Cellular infiltration in traumatic brain injury

A Alam, EP Thelin, T Tajsic, DZ Khan, A Khellaf… - Journal of …, 2020 - Springer
Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

S Leclercq, FM Mian, AM Stanisz, LB Bindels… - Nature …, 2017 - nature.com
There is increasing concern about potential long-term effects of antibiotics on children's
health. Epidemiological studies have revealed that early-life antibiotic exposure can …

Blood–brain barrier pathophysiology in traumatic brain injury

A Chodobski, BJ Zink… - Translational stroke …, 2011 - Springer
The blood–brain barrier (BBB) is formed by tightly connected cerebrovascular endothelial
cells, but its normal function also depends on paracrine interactions between the brain …

Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences

Z Redzic - Fluids and Barriers of the CNS, 2011 - Springer
Efficient processing of information by the central nervous system (CNS) represents an
important evolutionary advantage. Thus, homeostatic mechanisms have developed that …

Cerebral edema in traumatic brain injury: pathophysiology and prospective therapeutic targets

EA Winkler, D Minter, JK Yue… - Neurosurgery …, 2016 - neurosurgery.theclinics.com
Traumatic brain injury (TBI) is a complex and heterogeneous disorder with a tremendous
public health burden. It is grossly defined as an alteration in brain function or other evidence …

Current status of chemokines in the adult CNS

A Réaux-Le Goazigo, J Van Steenwinckel… - Progress in …, 2013 - Elsevier
Chemokines–chemotactic cytokines–are small secreted proteins that attract and activate
immune and non-immune cells in vitro and in vivo. It has been suggested that chemokines …

The choroid plexus in healthy and diseased brain

C Kaur, G Rathnasamy, EA Ling - Journal of Neuropathology & …, 2016 - academic.oup.com
The choroid plexus is composed of epithelial cells resting on a basal lamina. These cells
produce the cerebrospinal fluid (CSF), which has many functions including rendering …

[HTML][HTML] Role of microvascular disruption in brain damage from traumatic brain injury

AF Logsdon, BP Lucke-Wold, RC Turner… - Comprehensive …, 2015 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is acquired from an external force, which can inflict devastating
effects to the brain vasculature and neighboring neuronal cells. Disruption of vasculature is …