Background The degree of efficacy, safety, quality, and certainty of meta-analytic evidence of
biological non-pharmacological treatments in mental disorders is unclear. Methods We …

Depression is a prevalent psychiatric disorder that often leads to poor quality of life and
impaired functioning. Treatment during the acute phase of a major depressive episode aims …

Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …

Objective: To familiarize the reader with the role of electroconvulsive therapy (ECT) in
current psychiatric medicine. Method: We review clinical indications for ECT, patient …

Catatonia is a serious, common syndrome of motoric and behavioral dysfunction, which
carries high morbidity and mortality. Electroconvulsive therapy (ECT) is the definitive …

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We have known for nearly a century that triggering seizures can treat serious mental illness,
but what we do not know is why. Electroconvulsive Therapy (ECT) works faster and better …

Objective The main purpose of this review was to synthesise evidence on ECT's effects on
brain's structure. Method A systematic literature review of longitudinal studies of depressed …

Electroconvulsive therapy is the most effective treatment for severe, psychotic or treatment-
resistant depression. However, its effectiveness continues to be questioned, both in …

Background Electroconvulsive therapy (ECT) is still being administered to approximately a
million people annually. There have been no ECT versus simulated ECT (SECT) studies …