Fast-track development of vaccines for SARS-CoV-2: the shots that saved the world

VP Chavda, Q Yao, LK Vora, V Apostolopoulos… - Frontiers in …, 2022 - frontiersin.org
In December 2019, an outbreak emerged of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) which leads to coronavirus disease 2019 (COVID-19). The World Health …

COVID-19 and vaccination: myths vs science

VP Chavda, Y Chen, J Dave, ZS Chen… - Expert Review of …, 2022 - Taylor & Francis
Introduction Several vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …

Protein subunit vaccines: Promising frontiers against COVID-19

VP Chavda, ENHK Ghali, PC Balar… - Journal of Controlled …, 2024 - Elsevier
The emergence of COVID-19 has posed an unprecedented global health crisis, challenging
the healthcare systems worldwide. Amidst the rapid development of several vaccine …

Intraduodenal delivery of exosome-loaded SARS-CoV-2 RBD mRNA induces a neutralizing antibody response in mice

Q Zhang, M Wang, C Han, Z Wen, X Meng, D Qi… - Vaccines, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which causes
coronavirus disease 2019 (COVID-19), has presented numerous challenges to global …

Computational and enzymatic studies of sartans in SARS-CoV-2 Spike RBD-ACE2 binding: the role of tetrazole and perspectives as antihypertensive and COVID-19 …

K Kelaidonis, I Ligielli, S Letsios, VP Vidali… - International Journal of …, 2023 - mdpi.com
This study is an extension of current research into a novel class of synthetic antihypertensive
drugs referred to as “bisartans”, which are bis-alkylated imidazole derivatives bearing two …

Aged population and immunocompromised patients: impact on SARS-CoV-2 variants and treatment outcomes

VP Chavda, MT Chhabria, V Apostolopoulos - Biologics, 2022 - mdpi.com
Patients with an immunocompromised state are at risk of developing a long-term infection
from the coronavirus 2 that causes severe acute respiratory syndrome (SARS-CoV-2). It has …

How do we change our approach to COVID with the changing face of disease?

V Apostolopoulos, J Feehan… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction The emergence of SARS-CoV-2 triggered a global health emergency, causing>
7 million deaths thus far. Limited early knowledge spurred swift research, treatment, and …

Dose Intervals and Time since Final Dose on Changes in Metabolic Indices after COVID-19 Vaccination

A Alghamdi, K Wani, AM Alnaami, NM Al-Daghri - Vaccines, 2023 - mdpi.com
The rapid development and implementation of COVID-19 vaccines merit understanding its
effects on metabolic indices. This retrospective longitudinal study investigated the influence …

An oral vaccine for SARS-CoV-2 RBD mRNA-bovine milk-derived exosomes induces a neutralizing antibody response in vivo

Q Zhang, M Wang, C Han, Z Wen, X Meng, D Qi… - bioRxiv, 2022 - biorxiv.org
The severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) that causes the
coronavirus disease 2019 (COVID-19) has presented numerous challenges to global health …

BCG and SARS-CoV-2—What Have We Learned?

J Kulesza, E Kulesza, P Koziński, W Karpik, M Broncel… - Vaccines, 2022 - mdpi.com
Despite controversy over the protective effect of the BCG (Bacille Calmette-Guérin) vaccine
in preventing pulmonary tuberculosis (TB) in adults, it has been used worldwide since 1921 …